thyroid hormone resistance syndrome

[hand4jesus]

Hello and thank you.
I have been struggling to figure out what is wrong with me. My tsh levels are going up and up and up. A year ago my levels were 13 and 2 and a half months ago it was 47 then six weeks ago it was 61 and just a couple of weeks ago it is 68. The big question my doc has is are you taking your meds and I am and have been for 20 years. I know all the rules, no food for an hour after taking, no vitimins with pills. I am currently on 300 mg. I was surfing the net and came across this disorder. Thyroid Hormone Resistance syndrome. My doctor hasn't a clue as to why the meds aren't helping. I am now crushing the pills and taking them with apple sauce. I am so tired all the time. Depressed. Confused. I have gained over 90 pounds this year and everyone just thinks it is my eating and believe me I can't stop the weight gain.
Any input would be completely apprecated.
Thank you,
Luann Hand

[gimel]

Has your doctor ever tested for the thyroid antibodies, TPO ab and TG ab, to determine if that is the cause of your hypothyroidism?   Have you been tested for free T3 and reverse T3?  You really need to know the level of FT3, since it is the thyroid hormone that largely regulates metabolism and many other body functions.  Under some conditions the body can convert too much T4 to RT3, instead of T3. Since the RT3 is a mirror image of FT3, but is biologically inactive, the bottom line is that you end up with inadequate FT3 getting into the receptor cells and then you become hypo.  I think this is worth checking out before assuming it is Thyroid Hormone Resistance.

[olearyrie]

hey hun

i just found out i have this thyroid hormone resistant syndrome, only 1 in ever 50,000 people have it its really rare and not many doctors know what it is, you need to go to a specialist  that knows what this is so he or she can test u for it. im taking 350 mg and when i found out i had it they brought me down due to it effecting my heart but also taking this amount can effect ur bones ect u really need to go to a specialist as most doctors wont be able to treat u properly due to most not knowing what it is

hope this helps

[Barb135]

I'm not familiar with "thyroid hormone resistance", but maybe some of the other members are.  I'm sure someone will chime in with an answer.