I am a 21 year old female and have had bladder issues (pressure, urgency, nocturia, urethra burning/squeezing feeling, difficulty urinating) for two years that won't go away and seemed to have begun after I became sexually active. At first, the doctors thought it was a UTI but the antibiotics stopped working after a while. I've been to numerous doctors (PCP, urologist, OBGYN, gastroenterologist, neurologist, chiropractor) and had many, many tests - yet no one can figure out the problem. I was treated for endometriosis and HPV (high-risk, precancerous cells) last year in March and told I have dyssynergia and vaginismus. My brain MRIs show nonspecific white matter disease - but I'm told this is insignificant. I do not have nor have I ever had itching or any form of incontinence. I am told I do not retain urine and do not have interstitial cystitis. No other STDs, infections, etc. have been found. What could be going on?