Undiagnosed Symptoms Community
24.4k Members
Avatar universal

Can anyone tell me what these symptoms seem to be most likely caused from?

I am 59 year old female, very healthy all my life except granulocytopenia at 11 and acute epstein-barr diagnosed in 1997 (3 years to 2000).  Over the past 15 + years, I have been very active: karate, cross fit classes, weight and cardio training - very fit. The only flu I've had, even, was in August 2015.  In November 2015 I recognized an ongoing, persistant fatigue, generally not feeling well.  I gave up karate in January 2016 but continued my fitness classes & gym, as much as I could.  I had heart issues and some chest pain and shortness of breath, too.  I failed a stress test and was put on the drug protocol for that in October  2016 until I had the angiogram in November 2016 - all clear.  In April 2017, I had Rhabdomyolisis, maybe due to a cross fit routine I did (really minor to me, but we don't know what else could possibly have caused it)  ck levels went only up to 6000 and came back down to normal within a week or so.  I then recognized that I had musscle loss .. and that muscle loss continues, slowly, to this day. I had an EMG and nerve conduction testing in August 2017 that didn't show anything abnormal and I'm scheduled for another one in February.  I am having more difficulty getting out of a  chair, going upstairs, in and out of vehicles.  I also have general muscle aches, all over, and periodic specific pains  in my muscles and joints, including hands and fingers. However, ck levels are normal & blood tests, I'm told, appear to rule out autoimmune disorders and anything to do with thyroid.  The rheumatologist originally said he thought I might have  McArddles, but then said no, I couldn't have been as active prior to now if that was it.  I am also waiting to see an infectious disease specialist. I've had to sel my business as I cannot continue working.  Any thoughts of what else may not have been covered that I should be looking at?
2 Responses
1756321 tn?1499064984
Vitamin D deficiency needs to be ruled out. My mothers leg weakness was very bad due to this deficiency. Other symptoms for her included muscle and joint pain.  Optimal vitamin D levels are between 100 - 150 nmol/L (40 - 60 ng/ml).
1 Comments
I 'll look into that...thank you!
363281 tn?1518219421
COMMUNITY LEADER
Hello~Have they done an MRI to rule out MS, I understand this is one of the only way this disease can be diagnosed. Some of your symptoms point to that. It usually strikes between the ages of 20 to 40. I would ask your GP about this and see if he/she will give the needed tests to rule it out.

I hope you feel better soon. God bless you.
2 Comments
Waiting for an MRI.  Both MS and ALS have not been ruled out  but the doctors don't think it's either...now believe it's a metabolic or mitochondrial disorder.   I've had many more blood tests and genetic testing & am scheduled to see a metabolic disease specialist   so I think I'm finally on the right track...thanks for all the help!
Waiting for an MRI.  Both MS and ALS have not been ruled out  but the doctors don't think it's either...now believe it's a metabolic or mitochondrial disorder.   I've had many more blood tests and genetic testing & am scheduled to see a metabolic disease specialist   so I think I'm finally on the right track...thanks for all the help!
Have an Answer?
Top General Health Answerers
363281 tn?1518219421
Nelson, New Zealand
1756321 tn?1499064984
Queensland, Australia
19694731 tn?1482853437
AL
Learn About Top Answerers
Undiagnosed Symptoms Community
24.4k Members
36.2k Questions
Popular Resources
In this unique and fascinating report from Missouri Medicine, world-renowned expert Dr. Raymond Moody examines what really happens when we almost die.
Think a loved one may be experiencing hearing loss? Here are five warning signs to watch for.
When it comes to your health, timing is everything
We’ve got a crash course on metabolism basics.
Learn what you can do to avoid ski injury and other common winter sports injury.
Here are the pros and cons of the top fad diets and weight loss plans of the year.