Do you or anyone you know experience this? Do you have any information or advice that could help lead me to a diagnosis and relief? Here is my backstory & pertinent information:
Since mid 2010, I have been experiencing the following symptoms in my right lower leg:
*Excruciating leg cramps in my right calf, which are primarily nocturnal, but do occur sporadically during the day. On average, I have anywhere from 5-15 per night.
*Muscle twitching(fasculations), also primarily at rest & mostly confined to my lower right leg. On average, I have 75-100 twitches per MINUTE, most of which are not painful. Again, this mostly occurs after I have been resting for 10-15 min. You can visibly see most twitches as they occur.
* Constant soreness & the feeling that the calf muscle is tight. I stretch it often throughout the day to relieve the soreness temporarily & in hopes of avoiding the cramping. While it does work at times, it has not alleviated the cramping at night, nor has it reduced the number of cramps per night. The soreness & tightness is worst in the morning with the first several steps.
*The cramping & twitching has slowly, but progressively, gotten worse. Recently, I have begun having new, mostly mild, twinges of pain in my right back lower leg. These are not confined to my calf muscle & do not seem to have any rhyme or reason.
I have seen my internist, a rheumotologist, an orthopedic & a neurologist. I have been checked for the following serious conditions:
*Lupus
*M.S.
*Myositis
*DVT
*Compartment Syndrome
*Lyme Disease
*Fibromyalgia
*ALS
I do not have any of these conditions & didn't think it was a correct fit even before being tested for them. I have also ruled out the obvious causes of nocturnal cramping/charley horses, such as vitamin deficiency. The list of bloodwork & testing I have had done is very extensive. The MRI of my calf did show fairly significant muscle wasting, but we have been unable to pinpoint the root cause. I have a muscle biopsy scheduled for next month. The doctors have tried several medications/supplements & even home remedies, but so far none have worked.
Lastly, I have done extensive research online in hopes of finding a possible cause and/or solution to my symptoms to no avail. I have been unable to find anything which matches, or even closely matches my symptoms. I have gone through the MedHelp forums & haven't been able to find anyone with these exact symptoms only. As you can imagine, these painful cramps & the constant twitching has caused me to have very poor sleep, which is taking a toll on my body in other ways.
Please help! I am wondering if anyone has suffered from these symptoms or could offer any new advice or information which would help lead to a correct diagnosis.