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Avatar universal

Chronic bronchitis with ivig treatment

Hi thanks for reading everyone.

I have recurring bronchitis, sinus, uti and ear infections. Been getting them once a year until 6 years ago. Then they became more frequent in nature. So frequent with in the last 3 years I am most likely with an infection than with out.  I have been over prescribed, and over taken antibiotics; the standard ones seemingly are not working at all anymore.

I have been diagnosed with asthma (from birth), chronic bronchitis, recurring kidney stones, and  CVID receiving ivig for the last 9 months. Also on 3 kinds of asthma meds including Xolair. My igg level is now a constant 700-900. Blood Doc says my immune system is fixed. She is telling me this while I am coughing uncontrollably in her office. Then says it's got to be something else happening here, and sends me out the door.

My pulmonary doc has no clue, allergist has no clue. Does anyone out there have common issues maybe with some answers? Or lead me on the right path to what to investigate next. I don't want to just say this is as good as it gets, cause this *****.

Thanks
Nicki
5 Responses
1530171 tn?1448133193
Hey Nicki.

Hmm, there are a few... holes in your case. That's good news.

The IVIG infusion will not and cannot  address the entire immune system and to expect something like this-not you the patient, but the doctors- is borderline naive.
Upper respiratory tract infections which include sinuses, ear infections,
bronchitis, common cold, possibly asthma as well -depending the origin- etc. are mainly checked by IgA.
  IgG will not protect you enough from those. Your IVIG is IgG only!
Also the urinary tract is mainly protected by IgA.
So what the hematologist is saying is incorrect, unless there's other pertinent information missing.

The next observation is that you may have a yeast overgrowth/candida because of the antibiotics, stress and other factors.
Please follow my train of thought for a minute here:
It involves two main substances, methionine synthase and acetylaldehyde.
--The first one,methionine synthase, is a very vital enzyme, responsible for DNA repair and many other biochemical processes, directly or indirectly, requiring methylation.
--The second one, acetylaldehyde, a potent methionine synthase inhibitor,  is  a byproduct of Candida.
Conclusion: Candida inhibits Methylation. (Biological and mental stress also inhibit methylation)
Why is this relevant to you ?
- It might be very relevant because in undermethylation, it is common that you have low T cell production, higher B cell production with high levels of histamine and leading to increased allergies and autoimmune reaction.

Another consequence of undermethylation is elevated homocysteine, not a good thing at all (potentially toxic).
In your case this could explain the recurring kidney stones, as in circulation, homocysteine can interact with other homosysteine molecules forming single molecules called homocystine (not a typo) which may cause the kidney stones.

If all this sounds at first complicated, it is not. You just need to read it over
a few times till it starts making sense to you, unless you already have some background in this field.

There are a lot of things that can be done to improve some of these imbalances, however, the challenge is how to go about it in a dysfunctional medical system.
I'm never short of ideas, so please let me know what you think first and then we can explore various options.

I hope this helps shed some light, however, please note that my comments are not intended to replace medical advice.

Looking forward to your reply.

Best wishes.
Niko
1530171 tn?1448133193
Hey Nicki.

Hmm, there are a few... holes in your case. That's good news.

The IVIG infusion will not and cannot  address the entire immune system and to expect something like this-not you the patient, but the doctors- is borderline naive.
Upper respiratory tract infections which include sinuses, ear infections,
bronchitis, common cold, possibly asthma as well -depending the origin- etc. are mainly checked by IgA.
  IgG will not protect you enough from those. Your IVIG is IgG only!
Also the urinary tract is mainly protected by IgA.
So what the hematologist is saying is incorrect, unless there's other pertinent information missing.

The next observation is that you may have a yeast overgrowth/candida because of the antibiotics, stress and other factors.
Please follow my train of thought for a minute here:
It involves two main substances, methionine synthase and acetylaldehyde.
--The first one,methionine synthase, is a very vital enzyme, responsible for DNA repair and many other biochemical processes, directly or indirectly, requiring methylation.
--The second one, acetylaldehyde, a potent methionine synthase inhibitor,  is  a byproduct of Candida.
Conclusion: Candida inhibits Methylation. (Biological and mental stress also inhibit methylation)
Why is this relevant to you ?
- It might be very relevant because in undermethylation, it is common that you have low T cell production, higher B cell production with high levels of histamine and leading to increased allergies and autoimmune reaction.

Another consequence of undermethylation is elevated homocysteine, not a good thing at all (potentially toxic).
In your case this could explain the recurring kidney stones, as in circulation, homocysteine can interact with other homosysteine molecules forming single molecules called homocystine (not a typo) which may cause the kidney stones.

If all this sounds at first complicated, it is not. You just need to read it over
a few times till it starts making sense to you, unless you already have some background in this field.

There are a lot of things that can be done to improve some of these imbalances, however, the challenge is how to go about it in a dysfunctional medical system.
I'm never short of ideas, so please let me know what you think first and then we can explore various options.

I hope this helps shed some light, however, please note that my comments are not intended to replace medical advice.

Looking forward to your reply.

Best wishes.
Niko
Avatar universal
Wow that makes a lot of sense what you said. I have a new urologist I am seeing first week of December I am going to bring this up. And also I have not had my Iga checked in over a year!  

I have tried probiotics in the past but quite them cause I thought they were not doing anything. Naive at best back then about all if this.

You have given me a lot of new things to research and I thank you kindly for that and will most likely be back with more questions.

Sincerely
Nicki
Avatar universal
Well this is strange the drug used to treat candida is Diflucan. I just went through a round of that and I swear it made my cough better. The gp keeps telling me that is probably not the case. But I keep telling him he's wrong cause he's cool like that. But I have also been tortured with thrush at least 3 times this year.

You have out me on the right tract to ask the right questions.
1530171 tn?1448133193
Hey Nicki, funny I was just thinking about you.

Guess what? I had been thinking to mention to you my #1 recommendation
for candida treatment which is Organic Virgin Coconut Oil- I'm the local unofficial spokesperson for it in my area lol!
Recommended dosing-->  1T daily week 1,  week 2--> 2T daily, week 3 --> 3T etc., until you reach 6T daily /180 lbs, 5T/ 150 lbs or 4T/120Lbs<
along with an anti-candida diet.

Something to note is that Diflucan AKA Fluconazole can cause electrical changes in your heart called QT prolongation.
Your heart recharges after each heart beat measuring this from the start of the Q wave to the end of the T wave,
so in prolonged QT intervals the recharging takes longer.
Some symptoms could be serious and some people may have none, but again most people on short term small dose, Diflucan will never acquire QT prolongation.
Not to alarm you, but the coconut oil alternative is safer and more effective!!!
--- Ref: PMID:# 17651080 ---

You will never look back! Antifungal, antimicrobial, anti-inflammatory, anti-viral, anti-parasitic, ...Dare I say more? Well, just one more thing:

You may want to look into Oil Pulling with Virgin Coconut Oil-
I have been doing this every single morning ( OK I exaggerated, missed a couple times) for years.
Excellent method to prevent toxins and bacteria from entering your body from your mouth, leading also to superior oral health and hygiene and star-like wonderful healthy teeth!

If you need better supplemental immune support than coconut oil, I would have to think real hard to find one.

Glad to be of help.

Niko




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