I've never done this before so I'll do my best. I'm 39 going to be 40 next Monday, caucasian female. When I was around 30 I started having some joint pain in my left shoulder and knees, I was with Sutter labs at the time and the provider ran an ANA which was negative, didn't think anything of it. I started not feeling well almost 8 years ago after my son was born, joint pain, severe fatigue, insomnia increased. Chalked it up to a new baby. Then I had a rapid weight loss of about 30 lbs without trying which has NEVER happened to me anyway, the fatigue and pain increased, ANA screen returned positive with speckled atypical pattern I think 1:160 suspicious for SS-A/RO. Further testing later showed thyroid antiperoxidase antibodies over 1,000, started thyroid medication which decreased the levels. Spine degeneration with large Schmorls node at L4L5 mutiple bulging discs. After my daughter was born 4 years ago, symptoms increased to include gait disturbances, 2 falls on separate occasions with transient parathesias felt in face and extremities. Next ANA indicated homogenous pattern. Permanent numbness to L leg and part of foot extending to the great toe, I'm assuming from the spine? My last doctor before this one ordered an MRI which was abnormal, "high intensity foci on T2 and FLAIR in left middle cerebellar peduncle and in the white matter adjacent to the occipital horn of the left lateral ventricle. No definite lesions are identified in the corpus callosum". Referral to neurologist who recommended a spinal tap which resulted in oligoclonal bands in CSF, "multiple restriction bands that are also present in the patient's corresponding serum sample. Unable to define whether these gammaglobulins are of systemic or intracerebral origin". SO follow up in another year for MRI you probably don't have MS, but what the heck is going on?Most ANA is negative which shocked me to the core, though I know they can change. My B12 is chronically elevated, last one was 1,544, I don't take supplements and should be considering I am a gastric bypass patient. If anyone has any ideas I am all ears. I just feel alone. My next stop is a therapist. Thanks everyone for reading this.