Hi
Welcome to the forum!
Swollen hot hands with skin peeling could be due to celluitis or infection of the skin. It could also be due to hypothyroidism, eczema, psoriasis or contact dermatitis (due to soap, detergent, cleaning agents—basically anything that her hand comes in contact with). It is difficult to comment beyond this at this stage without examining. Please consult an skin specialist regarding this.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
How long has she has this condition? Has she seen a physician and received a blood workup with culture?