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The commonest cause of pain or a heat sensation in the calf is DVT or deep vein thrombosis and clots. This is best diagnosed by duplex ultrasound (color dopplar) or by angiogram. It can also be due to pinched spinal nerves in the lumbo-sacral area or a pinched nerve at the knee joint. A nerve conduction study should be done. A MRI of the lumbar spine should also be able to throw some light. A deep vein thrombophlebitis or intermittent claudication (spontaneous spasm and relaxation of arteries) can also cause similar symptoms. Infection of skin called cellulitis could also be a cause. It can also be infection of lymphatics.
At times it is also due to low sodium, potassium, magnesium or calcium in the body. Hence serum levels of these electrolytes should also be checked. Dehydration is another frequent cause.
Please consult your PCP for primary examination followed by proper referral.
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