Hi
Welcome to the MedHelp forum!
Yes, it is possible to have alcohol intolerance. Alcohol is rich in histamines. So if you feel its hormonal, then this is the cause. Anti histamines help take care of this. The other possibilities are intolerance to sulfites, gluten, yeast etc in the alcohol.
It could also be a hangover from the drink. If you get headaches at other times too, then the possibility of migraine too should be looked at. In your case alternatively, alcohol can act as a trigger for the migraine. Please consult an internal medicine specialist.
Hope this helps. Take care!
does this ever happen when you DON'T drink?