Hi Thanks so much for this forum. I am a 28 year old woman. Several years ago, I started having pain that was diagnosed as RSD. I was on a course of prednisone for about 8 months before settling on a diagnosis and treatment. During that time, I gained about 10-15 pounds. I developed horrible acne that I am still fighting, as well as dry, scaly patches on my neck, hands, and arms and am always tired. I am also cold intolerant, but have pretty much always been that way. It’s been over a year since I was weaned from the prednisone, but I am still gaining weight (up at least 30 pounds over 18-24 months). I increased my exercise over this time. I have always been active, but now I’m up to 40-70 minutes of cardio 4-5 times a week and 30-60 minutes of low weight, high rep weights 2-3 times a week. I tried restricting my food intake at one point to 1000 calories for over a month and eventually ended up with a dietician who placed me on a 1650 calorie diet 6 months ago. I continued to gain weight. My thyroid was enlarged to palpation with a bruit, so I had a full panel run. My thyroid uptake was slightly elevated @ both 6 and 24 hours (26.2% @ 24). My TSH as 1.25, my T3 3.1, and my T4 1.03. My doctor tells me to exercise more and my dietician tells me to see my doctor. Do you have any suggestions or causes other than thyroid issues? Could this be thyroid issue? Thanks for your help.