Before giving birth 2 years ago, I had a few UTI's in my life. I had normal symptoms and was treated effectively with meds. After having him, I became depressed and started Zoloft. Within a few days, I couldn't feel my bladder and had a hard time voiding. I also found out I had a UTI, but I had no symptoms at all. I was cath'd 3 days in a row. At one point, I had a PVR of 220 cc's. I stopped the Zoloft and my urinary issues seemed to subside, so they were blamed on the med. I then went on Prozac and did well. However, during the year that I was on it, I kept getting asymptomatic UTI's. I would find out when I went to the doctor for something else. I had no symptoms. I went to a Urologist and it was found that I had a PVR of about 115 cc's. All other tests (blood work, ultrasound, pelvic exam) came back normal. We thought it could have been the Prozac causing retention which caused UTI's, so I went off of it and a month later my PVR was 18. Subsequent PVR's weeks apart were 46, 14, and 56 (although that time was 30 minutes after voiding). I also have been negative for UTI's since going off Prozac. My depression is back so I am trying out Wellbutrin. A week after starting it, I had a PVR of 64.
My questions are: 1) Would you agree that my original issue was caused by the SSRI's since I had no prior problems that I was aware of and they seemed to improve after stopping SSRI's? I know that I did not have any UTI's during my pregnancy as I had routine urinalysis twice/week. I had a c section but had no damage to my bladder that I was aware of and voided okay for 2 weeks postpartum until I started the Zoloft.
2) Is there any med that can be taken to combat the retention if I have the same issue with the Wellbutrin?
3) At what point should I worry about damage from retention? If I am under 100, is it relatively safe to say that I will not have damage to my kidneys caused by reflux?
4) Could the SSRI's affected the feeling in my bladder so that I didn't feel the UTI's?