Urology Community
19.3k Members
Avatar universal

Please help... uti symptoms -negative urine test

Alright- ive been having UTI symptoms. Burning after peeing, urge to pee and I went to the doctors and they did a urine test but it came out negative. They checked me for STD's and then did urine culture and still negative for UTI. They did this again 2 more times and still a negative.  What could it be? I take AZO to help with the symptoms but after Im done taking them symptoms come back. I dont want to be dependant on this med. Anywho my doctor *****-all she has done is test my urine over and over and is not helpful at all. I cant see any other doctor but her because she is my assigned doctor at Kaiser.

The thing is I had these exact same symptoms 5 years ago. They tested me repeadidly for UTI by taking urine samples and it all came back negative but they would give me antibiotics for UTI and it would go away.

Do i have flank pain? Little, it comes and go not all the time.  I do drink TONS of water but this hasnt gone away-its been 2 months. I barely got an appt with my doc this coming tuesday.

Any suggestions on what this could be?
20 Responses
351246 tn?1379685732
Welcome to the forum!
Unidentifiable bacteria means the normal culture set by most labs cannot grow it. This needs special cultures which all labs may not be able to set up. Once the organism is identified then a sensitivity test is set up. This will give the antibiotic that the organism is sensitive to. Consult an urologist if possible regarding this and get the test repeated at a standard lab giving them the background. Organism like Chlamydia and Mycoplasma need special cultures and also are a part of the STD panel (done in your case—were these two covered?). The other possibility is tuberculosis. This can give similar symptoms on and off.
Allergy to food items excreted via urine is another possibility. Rule out diabetes too.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
Avatar universal
Oh my goodness, it's almost relieving to read that I'm not alone!  I have had isues with chronic UTI's over the last several years but most often the lab results come back negative.  I am always put on antibiotics and it seems to clear it up whatever it is.  But a few months later it happens all over again.  I am only 28 and otherwise completely healthy.  It's terribly frustrating and I feel like I just don't get any answers.  I was really beginning to feel like a nut and almost started convincing myself it was in my head!  Please update here if you find any additional information.  I go in next week for another follow up urine catch with my dr. and will get a referral to a urologist.  Here's to hoping for some answers
489228 tn?1291535054
Chronic Cystitis have low level bacteria that do no always show up on UA or standard cultures.  There are also some organisms that are more difficult to culture to culture out, require special testing etc, also.  The cultures we used today were developed 100 years ago to find and treat acute not chronic infections.  These are also based on colony count which again is for acute not low level chronic infections.

It is possible that you also have Interstitial Cystitis.  The symptoms of chronic cystitis and IC are almost identical.  The difference being that long term antibiotic treatment can control or if not cure the symptoms of a chronic infection but IC is incurable at this point.  Determining which you have requires a urologist that treats chronic uti's and IC>

There are however many coping tools to help with symptoms of IC and researchers are
finding more and more treatments to help.  How ever either way right now you have an irritated bladder and many of the self help things we use to treat IC can help you to feel better in the diagnosis process.  You can pm me for some direct links to help you!

I am an IC support group leader for MO and ARK, our group is called MOARK IC.
Our website has many articles that you may find helpful!

Just this week I have started an IC  and pelvic pain support forum here on Med-help
too.  We are brand new so new info we be added as we grow etc. but I encourage you to join us also.  


I hope that each of are able to find help and relief.  

Avatar universal
I have just gone through the exact same thing. You are not alone. SS of UTI for 3 weeks , Urine C & S negative but I KNOW MY BODY. There is something wrong. Got a RX for Cipro 500 BID x 7 days. Hope it helps.
Avatar universal
I hope you all can help me here...

I am 24 years old male. I am having this burning sensation after urination from July-2014. It been 8 months. I am all frustrated and depressed. I almost forgot how my feeling was before July-2014.

---Please read this-------
I first felt burning sensation on 20th July-2015, I thought it would go away automatically. I waited 2 days, nothing happened, then I went to a pharmacy and took potassium citrate syrup, I thought my urine was getting concentrated due to hot weather, I continued that not happened, then I went to a doctor (GP), did urine analysis & Ultrasound, nothing they found in urine analysis, but in ultrasound they found that I have bladder infection. Then my GP gave me medicines, I was unrecovered, then after 7 days my GP told me to meet an urologist, Then I showed him my previous report. The urologist told me to repeat urine analysis and uric acid test. But in these two test he found nothing. after seeing my previous ultrasound report he gave me medication for 10 days.
after 10 days I felt the same uncomfortableness but intensity was low. I went to my urologist again then he told me to repeat ultrasound (KUB). But this time he found that I have no infection in my bladder. My previous bladder line (infection) was gone.
So, this time my urologist gave me K-2 syrup. (told me to take 3 times per day-2 spoon everytime)
After 15 days,  No improvement.
This time he told me that I got prostate infection and gave me antibiotics for 45 days.
(Bactrim and Alfusin for 45 days.)
(bactrim: 2 times per day
Alfusin: 1 time per day)

I felt that my symptoms improved, the intensity of burning got decreased but still sensation was there.

So, I changed my urologist, went to the best and famous urologist of my country on 30th december-2014.
I told him what happened with me, everything. Then I asked him that do I have prostate infection?? He told I dont think so.
He asked me at the staring of this infection did I have any fever ???
Did I have any blood in my urine???
I replied I did not have those.
He then told me to perform Uroflow study test. And I did it and from the result he told me that my Urine flow was not good. Then he told me to do ascending Urethrogram test. As he thought I might have some blockage in my urine pipe. also he did urine culture and urine analysis + Ultrasound+ blood test Uric acid. But he found nothing. Even from the Urethro Gram test too.

---------  Then after these all test he told me finally that I have this problem due to my mind. He told me to keep my mind off from it. You will feel better. He also told me I would not give you any tablets or syrup for this.
I was very confident on what he told......
But still the problem is same...It is still happening. Burning sensation is still there somewhere.

Burning sensation: When my bladder is empty I feel nothing, When my bladder is full I feel no burning sensation,,,
but lets say 10 mins after urination, I start to feel this burning sensation and it stays for like 40 mins intensity becomes zero almost. And again after urination it starts to happen. and it has been happening from 8 months. But now I must say, its intensity is very low (Slight) as compare to what it was before at starting.
I feel almost normal....no fever, nothing from this.
But still you know hopeless and totally depressed. I want to be free from this sensation. Its very uncomfortable. Very very much.

I just want to know what it is.....
Bladder infection ???  Cystitis ???  UTI ???
Prostatitis ????
Acute Prostatitis ???
Bacterial Prostatitis ?? Non bacterial Prostatitis ??
Urethra problem?? Kidney problem?? Stone ???? Bladder stone ???  STD ???
or finally what the last urologist told me...Urine burning sensation due to mind ???????

Please help me......................

Please help me man Jks Lady
15319191 tn?1439827661
Im having the same issues. EVERY morning (for the past month or two) I wake up and I have a burning sensation after I pee and it lasts for about 1-2 hours after I pee ( I have to take acetaminophen) to take away the burning pain. After that I feel fine. I went to my doctor and she gave me a urine test, and it came back negative, she also sent it to a lab and it came back negative. I don't know whats going on, but its making my life miserable, especially if I have to keep taking pain medication to take away the pain. I've been so frusterated I've looked at every possibility including worms in my system, that's how desperate I am to find an answer, even looked into Pancreatitis cancer. Im so tired and exhausted of this run around. Im starting to think it might be bladder cancer, but I'm sure they would have seen the cells in the urine test (hopefully!) but probably not. Its a headache, and I want it over with.
Just started to read this forum.  I have the same problem but I noticed it was lack of potassium since a little sweat seemed to lower my potassium... try to have your potassium level checked.
Have an Answer?
Top Urology Answerers
11369760 tn?1449507972
Southwest , MI
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Dr. Jose Gonzalez-Garcia provides insight to the most commonly asked question about the transfer of HIV between partners.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.