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Urine drug screen result of "substitute"?

I just had a recent drug screening with a result of "substitution", what would cause this? I have ongoing urology and cardiac issues that I'm curretly undergoing testing for; I have chronic UIT's (since I was about 12, occurring at least oncce/month and frequently lasting several weeks or more) and I haven't been told the results of the cardiac testing yet, aside from MVP which I believe is fairly common in women. Also, my diet has been very poor the past few months too, I've been under a considerable amount of stress lately and have had the flu twice in two weeks so I have only been able to eat some cereals, breads, and drink milk without feeling sick to my stomache. Any ideas or cause for concern?

This discussion is related to low creatinine reading.
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