Thank you for your advice.
Hello,
Vagifem can cause headaches in 9% of the people as its side effect. It can also cause abdominal pain, genital moniliasis, vaginitis and vaginal discomfort. It can also cause insomnia or hot flashes. Hence I suggest you to get this drug changed to some other estradiol tablets for atrophic vaginitis.
I hope it helps. Take care and regards.