On 4-6-10 I had bladder biopsy surgery, on4-5-10 dr.found infection in bladder,took 2 cipro tablets that date . When culture came back on 4-8-10 dr.called me and put me on Nitrofurantoin MCR 50 mg C, 4 per day for 5 days and then l bedtime for 30 days. Biopsy received and diag: chronic follicular cystitus. "Sections reveal urinary bladder mucosa. Urothelium shows normal maturation pattern.Unerlying small cystic areas present lined by benign-appearing urothelium. Lymphoid aggregate with germinal center formation present within mucosa. Atypia is not seen. Will this problem return even though I am on antibiotics? Thanks for answer.EB,North Carolina
Hi,
Follicular cystitis (cystitis follicularis) is a non-cancerous lesion which results from chronic bacterial infection. It is nothing but chronic cystitis characterized by small nodules due to lymphocytic infiltration.
Treatment options for this are limited and may overlap with those for interstitial cystitis. Pentosan polysulfate sodium and dimethyl sulfoxide are approved for the treatment of chronic cystitis and may be of benefit some patients.
I the urological investigative workup is not forthcoming, one must consider a rheumatological work-up, including TSH (thyroid stimulating hormone), Eythrocyte sedimentation rate, Anti-nuclear anti-bodies and rheumatoid factor levels.
Follow-up with your primary physician is essential.
If you have any further queries do get in touch with me.
Regards,
Dr Sylvester