Highly unlikely. There is really no supplement that will help you lose weight and keep it off except those that increase your metabolism, and that will be temporary as well. This is just an amino acid supplement with colostrum, which is a very odd thing to put in a weight loss product. This substance is naturally only found in the first batches of mother's milk of mammals and helps to build an infant's immune system. Have no idea how it would help you lose weight. If you truly want to lose weight and keep it off, change your diet, exercise more, expect slow results, and stick to it as a permanent change. You will do better eating moderate amounts of meat, eating fish, veggies, and whole grains and legumes. But do your own research. The only way I can see this helping in the long-term is if you also start a weight lifting program at the same time, as it might help with muscle building somewhat.