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Azor and grapefruit
can I eat grapefruit while taking Azor
Hello caregiver222,
Just wanted to tell you I enjoyed reading your comments about eating
grapefruit. I'd heard that you're not supposed to eat grapefruit when
you're taking certain drugs. I didn't know the reason why though.
Now I do. Thank you. Eve
Just wanted to tell you I enjoyed reading your comments about eating
grapefruit. I'd heard that you're not supposed to eat grapefruit when
you're taking certain drugs. I didn't know the reason why though.
Now I do. Thank you. Eve
Good question. I would ask your family doctor if you can eat grapefruit
while taking Azor. With some drugs, eating grapefruit is actually dangerous.
while taking Azor. With some drugs, eating grapefruit is actually dangerous.
No. Any grapefruit causes the liver to stop producing CYP 450 super-enzymes. These are necesssary to metabolize many drugs. Thus, at a minimum the drug will have no effect. Twenty-four hours later, the drug is still in the blood (unmetabolized) and you take a second dose. At this time the CYP superenzymes again begin to be produced sand you end up with too much of the drug metabolized. One issue is "how much grapefruit is necessary to affect the liver?" A single grapefruit is enough. This is why many medications say "do not take with grapefruit juice".
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