It has now been 15 months since my last Depo shot and still no AF. My doc gave me Provera, but I didn't have any withdrawal bleeding after taking the last pill. When I told my doctor this, she said that my lab results showed that my prolactin was high, and so she prescribed something to bring prolactin down. My question is, what does the prolactin have to do with low estrogen? I've read that if you do not bleed in response to Provera, you have low estrogen, and should be given estrogen along with the Provera. My doctor gave me something else instead, so that would make me believe my estrogen level was ok, if that's the case, shouldn't I have bled after Provera? I just don't want to waste my time taking medication I don't need.