I have been taking the Depo-Provera shot for over a year now. I am a 33 year old. I have 2 children, 10 years old and 7 years old, and have hot flashes during the day, and worse at night, along with cold sweats. The reason the doctor insisted on the depo was because of maternal family history of estrogen-fed breast cancer. My question is whether the depo shot is inducing menopause hot flashes, or do I need to be concerned about other things, such as cancer. One sign of cancer is night sweats. I also have unexplained bruising sometimes.