Medical professional here at a loss;
Recently a family member of mine started TriNessa. History wise she is mildly hypotensive at baseline and takes metoprolol for rhythm control.
Her resting bp is 90/50, resting heart rate 40-55, pvc burden 6%. This is with metoprolol, which has been successful at suppressing symptoms.
Since starting trinessa however the following has been noted;
A return of symptomatic PVC's and effective loss of burden control Metoprolol observed at home.
Parasthesia in very specific regions well established as inmervated by cranial nerves, particuarly around the trigeminal.
Has anyone ever heard of these before? Studies I was abke to locate were pretty limited but suggested an increase in SVT incidence. Parasthesia was listed as an extremely rare side effect by the manufacturer, but the locations are very atypical.
I did see some information regarding an interaction between metoprolol and this product, but it pointed to an increase in metoprolol bioavailability, which theoretically shouldn't adversely impact the PVC burden?
Anyone have any input or knowledge.. Even similar personal experiences with this?