Is cirrhosis excluded?

[me_just34]

does a Doppler ultrasound  with the normal result except grade 1 hepasteatosis  exclude cirrhosis?
From time to time when i gain weight my alt level increases

[CHIN_C]

Ultrasound provides a rough assessment of liver size, contour, texture, and lesions: In terms of size, it tends to underestimate overall liver size and it is difficult to compare the relative size of liver lobes (which is important because cirrhosis can present with relative hypertrophy of caudate and left lateral lobes). In terms of contour, it may detect significant irregularity but may miss subtle irregularity. In terms of texture, it can suggest fatty liver but can sometimes overestimate this. In terms of lesions, it can detect large lesions but may miss small lesions. For more comprehensive evaluation, consider liver protocol CT or MRI abdomen with and without contrast.

[amit_22]

yes it is excluded. US + blood tests

[flyinlynn]

Ultrasound can confirm cirrhosis that is diagnosed by other means. It is not normally a stand alone method to confirm or deny a cirrhosis diagnosis.

There are many causes for elevated liver enzymes from aspirin to heavy exercise and as you mentioned NAFLD (non alcoholic fatty liver disease) can also cause elevations in ALT.

Many different conditions can raise ALT blood levels, so other testing is usually needed to interpret an abnormal ALT result.

To confirm cirrhosis the gold standard is a liver biopsy. Other less invasive options are a Fibroscan test somewhat similar to an ultrasound. Another test is a Fibrosure blood test. Those tests can diagnose cirrhosis as well.

Other blood tests that could indicate liver cirrhosis are a liver platelet count or INR test for how fast your blood clots.

I got this from the Mayo Clinic web page on how to diagnose cirrhosis.

"People with early-stage cirrhosis of the liver usually don't have symptoms. Often, cirrhosis is first detected through a routine blood test or checkup. Your doctor may order one or more laboratory tests that may suggest a problem with your liver, such as cirrhosis.

Liver function. Your blood is checked for excess bilirubin, which is a product of red blood cells breaking down, as well as for certain enzymes that may indicate liver damage.
Kidney function. Your blood is checked for creatinine as kidney function may decline in later stages of cirrhosis (decompensated cirrhosis).
Tests for hepatitis B and C. Your blood is checked for the hepatitis viruses.
Clotting. Your international normalized ratio (INR) is checked for your blood's ability to clot.
Your doctor may order imaging and other tests to further diagnose cirrhosis:

Magnetic resonance elastography or transient elastography. These noninvasive imaging tests detect hardening or stiffening of the liver and may eliminate the need for a liver biopsy.
Other imaging tests. MRI, CT and ultrasound create images of the liver.
Biopsy. A tissue sample (biopsy) is not necessarily needed to diagnose cirrhosis. However, your doctor may use it to identify the severity, extent and cause of liver damage."

The best person to determine what tests you should have to determine whether or not you have cirrhosis is your doctor. Have you discussed this matter with your doctor? What has your doctor said? Is there a reason you suspect you may have cirrhosis other than your intermittent slightly elevated ALT?

Just to add it generally takes many years to decades of insult to the liver to cause liver cirrhosis.