High ALT while on Tenofovir treatment

[melcul]

I would like to ask if anyone had any similar experiences while on nucs.
I've been taking tenofovir for 15 months now and ALT seems to have been stabilized at around 50-60.
The doctor didn't say anything about it, just that the "medicine is working"
I got to check my results for the first time in a year and I was quite disappointed that all I got from him was that I'm doing fine all this time, and never addressed this, as I find it extremely important.
Kidneys seem to be "ok" egfr >90
Folate is low
TSH 6.3 (<4.5) with normal T4 (2 months ago)

[stef2011]

after using peginterferon i had thyroid damage, i never developed autoantibodies or ultrasound abnormal results.i found out it is best not to treat subclinical hypothyroidism and my tsh slowly lowered from a pick of 9 to around 5 (max level of normal here).FT4 was slightly abnormal few times.i used t4 drug during peg treatment and for 1-2 years after that and it made a lot of side effects of hyperthyroidism.
TSH test cannot be used to diagnose hypothyroidism, they finlly published the study this year, only low ft4/ft3 can

so i suggest check autoantibodies, be sure vitd25oh is maximum range of normal to prevent autoimmunity and follow both ast/alt, thyroid, bones and kidneys during treatment

[ssdpositive]

Hi Melcul,

My AST before starting treatment was 52. I meeting to doctor next week. If she ask me to test it. I will let you know the result. I am on nucs since March 2021