CMIA / ELISA :: Which is more accurate?

[mhlorhan]

I was tested for Anti-HCV. Results: borderline -ve.(ELISA)

I was again tested for Anti-HCV one month after the first. The results: -ve.(CMIA)

I was a little worried and wanted to ask which method is more accurate?


This discussion is related to HCV Positive or Negative.

[anambr]

In addition to being more sensible than ELISA, CMIA is also a lot more specific.

So, your ELISA+, followed by CMIA- probably means you´re really anti-HCV negative, but ELISA's "oversensibility" and lack of specificity gave you a +.

You can relax... If you were really + for HCV, your CMIA would have shown so. ;)

[jon58]

Is  cmia still more  accurate that elisa and why?

[anxiety55]

CMIA is more specific than ELISA. I have exactly the same story as you.... ELISA +, CMIA - and 3 times PCR -

[jmjm530]

Of course, consider a better choice of words :)

[jmjm530]

LIke JP says, you need a PCR which is also called a viral load test. Tell your doc to quite screwing around and give you an accurate diagnosis.

-- Jim

[mhlorhan]

The result for me was:

Result :: 0.05            Cut off Value :: 1.0 (CMIA)

[JennyPenny]

Sorry....I meant to ask if the CMIA test gave you a number result or just said <5? I'm not positive but I think the CMIA is more sensitive than the ELISA. Someone will correct me if I am wrong.

[JennyPenny]

Instead of worrying why don't you have a PCR? At least you will be sure if you have the disease or not. If you are ELISA positive and PCR negative, you can always do a RIBA to confirm if it is a false positive or you fought off the virus yourself.