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Methylation defects the cause of desease

Mar 15, 2015 - 2 comments













auto immune







I was in treatment for candida for over a year. Over a 3 - 6 month period during treatment I noticed that my nerve pain was getting increasingly more painful and more frequent. My husband was having problems with his asthma getting gradually worse. I happened to stumble upon an article "Methylation Problems Lead to 100s of Diseases" by Suzy Cohen.

We had our genes tested through 23 and me and then went through genetic genie to have our raw data deciphered. Genetic genie sent us a panel on our methylation profile as well as our detox profile. It helped us to understand a lot of what was going on for the past 10 yrs or so.

We both have many defects including a defect in our CBS enzyme and this prevents us from braking down sulfur. It also causes us to produce to much ammonia along with histamine. All of the sulfur based supplements we were taking were slowly destroying us. Sulfur is suppose to be good for you but not when you have these active mutations.

We went on a strict low sulfur low protein diet. We take molebdenum (which we were already taking not knowing this was helping quite a bit), yucca to lower ammonia, L-carnitine to help lower ammonia and help with ATP energy, CoQ10 helps with the energy starved mitochondria, D-Ribose 3 times a day for energy, Hydroxy B12 because this is the only b12 we can tolerate until the sulfur and ammonia levels come down (we are deficient in b12), PQQ to help regenerate cells also an antioxidant,  Reversotrol - antioxidant, Pyridoxal 5' - phosphate B6, vit E, vit. D 5000, vit C, manganese, magnesium and potassium for electrolytes that are depleted, Creatine everyday, charcoal daily to help remove excess ammonia, bentonite clay and fiber to help remove ammonia and other toxins, Dandelion rt. in small amounts because it is a high in sulfur ( cannot take milk thistle because it is higher in sulfur than dandelion rt.) and histame or DOAsin to help lower histamine. We have other supplements but the ones I listed are the most important.

We have seen many benefits with the diet and supplements. It will take some time before we can actually start supplementing with methyl b12 and methyl folate. Once we are able to do this most of our health problems will go away. You can read more about these genetic conditions on DR Ben Lynchs Web site or go to Amy Yaskos web site on the methylation pathway.

I found out about this just when I was getting a little discouraged. Having the knowledge and treating these conditions has really improved my outlook on getting better . I hope everyone who has any kind of illness looks into this. We were very depleted in our nutrients. Treating this condition is going to turn it around for us as it can for many of you. Nerve pain, blood sugar instability, insomnia, fatigue, indigestion, migraine headaches, muscle sorendess, viruses, candida infection or other infections can all be signs of B vit. deficiency along with deficiency in other vitamins. Treatment of the methylation pathway is the future in medicine.

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535822 tn?1443976780
by margypops, Mar 19, 2015
Hi donjoe..I thought I had Lyme disease a while ago, I seem to get all symptoms now and again, then I thought it maybe CFS ...I have been diagnosed with pre diabetes but dont think I have that .I am low in Vit D and thats all they have found other wise...I have had flu twice this year and it was nasty,one conclusion I have come to is that the aerial spraying they are doing here in CA is making many of us sick with allergy like symptoms that come and go, I am surrounded by a lot of Yucca and Joshua trees and cactus so thats another possibility..I was bitten by a tick about 20 years ago ,and 3 weeks later had a really bad headache and other symptoms the Lyme has always been in my mind .

1353650 tn?1429463374
by donjoe341, Apr 16, 2015
Hi Margy
I think it is all of the above.
I have problems in my methylation cycle. My genes for detoxing are defective along with my genes for absorbing b12 and folate.
This set me up for the health issues I currently suffer with. I treated lyme, babesia and micoplasma for 3 years with not much improvement. I also have been treating candida overgrowth. Every time I tackle any issue by taking supplementation to kill the bacteria or fungus I feel really bad. It is likely that I have a very difficult time detoxing the poisons these organisms are giving off. I decided to go very healthy.
My diet consists of complex carbs only, no flour, no sugar, no processed foods, no caffeine, fresh veggie juice only, lots of filtered water, probiotics daily, fresh veggies cooked or raw, organic as much as possible, kombucha, kimchi, supplements that provide electrolytes, d-ribose, l-carnitine, CoQ10, creatine, and molebdenum (molebdenum helps with toxins caused from candida die off), vit E, Vit. D, good fats, HCL with betaine and gentian (before each meal), have helped me greatly.

I recently ordered glutithione patches to help me detox. I think this is my missing link since I am so deficient.
This is something you should consider especially with the toxic pesticides in your area.
I too suffer with insulin resistance (prediabetes) along with my husband and son. Our doctor that discovered this was very concerned because she said that we likely suffer with some kind of bacterial infection causing this problem. She told us to go to an infectious disease doctor. We did that for 3 years and got no where. This is because most medical doctors today do not believe in looking for parasites or candida. They do not treat the body as though it all works together. Testing is very poor for most bacterial infections like lyme. They just want you to pop antibiotics and think that is going to take care of things. Well it sure as hell doesn't. If anything it made things worse and candida harder to kill.

We have been making progress but always go backwards when we try to attack candida or any other infection with herbal supplements. Our bodies can not handle it. So, this is where glutithione comes in. Once we have done the glutithione for a few months we will then try to attack possible parasites along with candida.  I will let you know how it goes.

Also, I know you think that you do not have prediabetes because it doesn't seem possible. Some things are out of your control. My husband is stick thin and eats very healthy and was diagnosed with this. Most doctors would pass this off as genetic until they saw us all having the same condition at the same time. They can't figure it out nor do they try. Whatever you do, do not ignore it otherwise you will be just like all of the other Americans suffering from diabetes.
The best thing I could tell you to do is to try the glutithione patches for a few months and see how you feel.


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