May 21, 2009
Ankylosing spondylitis is an autoimmune condition that causes chronic inflammatory arthritis primarily affecting the spine.
Ankylosing spondylitis is most likely a multifactorial condition, which means that it involves a combination of genetic, lifestyle and environmental factors. It is currently well established that ankylosing spondylitis also runs in some families. Researchers believe that there are probably a number of genes that affect the development and symptoms of ankylosing spondylitis.
For example, the association between HLA-B27 (a variant of the HLA-B gene) and ankylosing spondylitis is one of the strongest known relationships between a MHC (major histocompatibility complex) antigen and a common disease.
For more information about the genetics of ankylosing spondylitis, visit: http://AccessDNA.com/condition/Ankylosing_Spondylitis/41