Bumetanide

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

This medication is given by injection into a vein or into a muscle by a health care professional. Follow your doctor's directions carefully. Dosage is based on your medical condition and response to treatment. Do not increase your dose, use this more often than prescribed, or stop using this medication without consulting your doctor. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. If you use this drug too close to bedtime, you may need to wake up to urinate. Therefore, it is best to use this medication at least 4 hours before your bedtime. Consult your doctor or pharmacist if you have questions about your dosing schedule. If you are giving yourself injections at home, learn how to prepare and inject this medication properly. Ask your doctor, pharmacist, or nurse any questions you may have about how to give yourself bumetanide. Learn how to store and discard needles, medical supplies, and any unused medication safely. Consult your pharmacist. Never reuse needles or syringes. Tell your doctor if your condition persists or worsens.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medication because very serious interactions may occur: cisapride. If you are currently using this medication listed above, tell your doctor or pharmacist before starting bumetanide. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amphotericin B, corticosteroids (e.g., prednisone), digoxin, ginseng, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, indomethacin, naproxen), probenecid, drugs that can cause hearing or kidney problems (e.g., cisplatin, aminoglycoside antibiotics such as gentamicin). Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or cause swelling (edema). Ask your pharmacist about using those products safely. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day). Consult your doctor or pharmacist for more details. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Do not share this medication with others. Dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about the dietary changes that might benefit you. Laboratory and/or medical tests (e.g., blood mineral levels such as potassium, kidney function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: an unusual increase in urination followed by a severe decrease in the amount of urine, severe weakness, weakness on one side of the body, slurred speech, sudden vision changes, fainting.

Before taking bumetanide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease (an inability to make urine), severe liver disease. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver problems, untreated mineral imbalance (e.g., low blood levels of sodium or potassium), gout, irregular heartbeat (e.g., ventricular arrhythmias), loss of too much body water (dehydration). This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If you have diabetes, bumetanide may infrequently make it harder to control your blood sugar. Monitor your blood sugar levels regularly and share the results with your doctor. This drug may reduce the potassium levels in your blood. Ask your doctor about adding potassium to your diet. Your doctor may prescribe a potassium supplement. Before having surgery, tell your doctor or dentist that you are taking this medication. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be more sensitive to the effects of this drug such as dizziness. Newborn babies, especially those that are severely ill or have a certain liver problem (jaundice), may be at greater risk for serious side effects (brain damage caused by too much bilirubin in the blood - kernicterus) while using this drug. Consult the doctor for more details. During pregnancy, this drug should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

This medication is expected to increase urination. Dizziness, headache, tiredness, nausea, or pain/redness at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may lead the loss of too much body water and minerals (including potassium), causing dehydration. Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration or mineral loss: muscle cramps/weakness, confusion, severe dizziness, drowsiness, unusual dry mouth/thirst, nausea/vomiting, fast/irregular heartbeat, unusual decrease in the amount of urine, fainting, seizures. Tell your doctor immediately if any of these rare but very serious side effects occur: decreased sexual ability, chest pain, hearing problems (e.g., ringing in the ears, hearing loss), easy bruising/bleeding, stomach/abdominal pain, yellowing eyes/skin, dark urine, sudden loss of consciousness. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

This is a very strong medication. Using too much of this drug can lead to serious water and mineral loss (dehydration). Therefore, it is important that you be closely monitored by your doctor. Tell your doctor immediately if you become very thirsty or confused or if you develop muscle cramps/weakness while using this medication.