For about 18 months I have been having on and off mid upper abdominal pain, last 2 months nearly constant, chronic constipation, slightly relieved with fiber pills, sometimes only 2-3 bm's per week. Also have an unexplained 25 pound weight loss in 6 months, from 130 lbs to 107 lbs. Also have chronic fatigue, slight anemia, and migraine headaches, as many as 20 migraines per month. I recently was tested for Celiac disease and my lab results were negative. IgA 247,anti-tTG 3, IgA gliadin 15 and IgG gliadin 8, also have slightly elevated Lipase 64. I am not a drinker either. I have not had an EGD done, and colonoscopy was normal. Are there many false negatives with having Celiac disease? Also if not Celiac disease any idea of what it might be? I am an RN who works 7pm to 7am three days a week. I hope this is enough info for you to give me a clue as to what is wrong with me, I am at my wits end