A high C-Reactive protein can be an indication of infection, inflammation, dental problem, arthritis, increased risk of heart problems, increased risk of cancers etc. A high C-Reactive protein should be evaluated ASAP.
High CRP with red swollen rashes could be due to inflammation of veins or vasculitis. Vasculitis is basically inflammation of arteries and veins. This includes cutaneous small-vessel vasculitis which affects skin, & kidneys; Wegener's granulomatosis which affects nose, lungs, kidneys; Churg–Strauss syndrome which affects lungs, kidneys, heart, skin; Kawasaki disease which affects skin, heart, mouth, eyes; Buerger's disease which affects leg arteries and veins. Diagnosis is by demonstrating increased erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), antineutrophil cytoplasmic antibody (ANCA) levels, white blood cell count and eosinophils. Anemia is also present along with hematuria or blood in urine. Blood vessel inflammation in the biopsy of involved organ or tissue, such as skin, sinuses, lung, nerve, and kidney confirms diagnosis. Treatment generally involves steroids and immunosuppressive drugs. Please consult your PCP for primary examination followed by proper referral.
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