Autoimmune, low T3 (conversion) or parathyroid

[LPitt]

I posted this in the thyroid forum as well because I'm not sure where I'm headed with my results.  Appreciate any input.


Hello. I have experienced a multitude of symptoms for years with my biggest complaint being extreme fatigue.  It is life altering and if I can muster to get through big events, I am unable to function for days.

I've been tested for everything, thyroid, autoimmune, Lyme but mostly everything is normal.

I've suspected thyroid because I am one of the lucky ones that gains weight and can't lose and hypothyroid is really the only possibility based on my tests that doesn't cause weight loss.

Other symptoms -- constipation, hair loss, irritability, tingling (hands and feet and even nasal/face more recently), dry skin, eye issues (dryness and tearing (think inflamed tear duct, comes and goes), forgetful, unfocused.  There are more, but these are main issues.

I've had low vitamin D (9),  borderline low bit b12 (210), high ANA from 1:80 to 1:640 with NO other autoimmune test positive (tested for RA, sclero, sjorgens, autoimmune thyroid etc).

My TSH is typically around 2, but occasionally 1.6 with my last TSH (with reflex to T4) the lowest EVER in 10+ years at 1.23 (not sure if this is the reg TSH test or if the reflex is different and that's why the result is unusual).

My last FT4 was 1.1 and my last FT3 was 2.7 with a RT3 at 17.  My TSH at this time was 2.0. This made my T3 /RT3 ratio at just under 16, which upon reading thought might explain symptoms, but doc says my results are all normal and true they are all in the normal range.

Finally, I have two serum calcium readings at 10.0 and 10.1.  I also had a flagged high urine calcium oxalate at the same time.  I questioned this but my doc told me that they were fine b/c my albumin level was above 4 so that meant the calcium was actually lower.  Is that true?  

I found parathyroid.com when searching low Vit D and high urine calcium.  It says calcium should be in the 9s if you're over 35 but I can't find anything about adjusting the reading for albumin so don't know if that's already accounted for.  Strangely, even the reading I had for calcium that was 9.8, my albumin was exactly the same as when it was 10 and 10.1.  Shouldn't the albumin change if the calcium changes?

The other thing that is new is I've started having high blood pressure, which I've never had.  Most often it is high systolic, but can be both.  I have a physical in a few months so will see what my doc says about that then, but since this is new and I have no idea why, just though I would mention it.  

I don't care what it is -- autoimmune, thyroid, parathyroid but I feel like I keep throwing things at it without really knowing.  I've taken Vit D, B12, plaque nil.  I've stopped for about a month or two as I just want to see where my own body takes me.

Any suggestions where now?  Thanks for reading this and I appreciate any thoughts.

LP

[LPitt]

Sorry.  That was meant for the thyroid forum responses.   I would still like autoimmune input.

thanks,
LP

[LPitt]

Thanks for your replies.

I have taken b12 and Vit d3 for years with no symptom improvement. I stopped the Vit d a couple of months ago b/c I thought it might be causing the high calcium.

My TPO  was negative, no value given, so I assume nothing was seen.  I've had every rheumatologicall test and EVERYthing is negative except the ANA, which has only gotten to 1:640 but tends around 1:160.

Pernicious anemia was ruled out with an mma level.  

My TSH has been around 2 give or take for 10+ years.  My FT4 has ALWAYS been 1.1.  I have at least 7 tests over 10+ years and it has always just been 1.1.  My FT3 has been around 2.7, but I have only a handful of these.

12 years ago my doc did a total t3 and a t3 uptake.  The total was flagged HIGH and the uptake was flagged LOW.  Doc didn't know what that meant so said it was all normal.  These are outdated tests and I have no idea what they mean.


So my last tests (all same time):

TSH. 1.92.   0.4-4.4
FT4.  1.1.     0.8-1.8
FT3.  2.7.     2.3-4.7

Single, most recent TSH (with reflex) . 1.28.   0.4-4.4

In 10+ years I've never had a TSH lower than 1.8, so not sure what that is.  My BP is usually 120/70-130/80. But I got a 155/95 at doc and at home it's consistently high, esp. the systolic.  

What other tests should I have?  How do you rule in/out central hypo (I have no idea what this is, so I will read up).

I'm seeing a new doc in a few weeks so I'd like to make my case, support it, and get any additional blood work/tests.

Thanks for your help.

LP