er pr weakly positive in tumour biopsy , not body, will armidex benefit?

[nidhi30]

My mother's initial reports stated her er-. pr- and hr1, she had had neo-adj chemo , masectomy and radiation, the tumour biopsy states that the tumour is weakly positive for er, she has been advised armidex. it was a locally advanced cancer. thinking if armidex will benefit, is it worth the side affects.


This discussion is related to er pr her-2 nue negative test results.

[nidhi30]

if anyone had a similar scenario, pls do guide me on this with your experience.  

[zouzi]

Hi,
Yes, I think that your mom would benefit by taking Arimidex.
If the tumor was estrogen receptive (even if weak)and the cancer was locally advanced,I think that it's best to follow the recommendation given by her Doctor.
Arimidex is an aromatase inhibitor.It works by blocking the enzyme aromatase (found in the body’s muscle, skin, breast and fat) which is used to convert androgens (hormones produced by the adrenal glands) into estrogen.  By eliminating estrogen, cancer cells that have positive estrogen receptors cannot grow.
Side effects are certainly not pleasant to anyone,but it has been proven that Arimidex can lower considerably a cancer recurrence.
Best wishes to both you and your mom.