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can you please explain this?
by jinkz, Mar 18, 2008 10:26AM
can someone help me to explain this?
this is my mom's laboratory result after she undergone a lumpectomy and i wanted to understand it clearly.
Pathologic Diagnosis:
Excision Biopsy, Breast mass, Right:
-INVASIVE DUCTAL CARCINOMA
gross description:
the specimen consists of an irregulary-shaped, brown-yellow firm mass measuring 3.7 x 2.7 x 1.7 cm. Sections disclose gray-white mottled cut-surface with an ii-defined, opaque, white-brown central area measuring 1.5 cm in widest dia. Rep.
microscopic description:
Microsections of the breast mass disclose dilated ducts solidly filled with neoplastic ductal cells having large, ovoid pleomorphic nuclei and moderate, eosinophilic, polygonal cytoplasm. These cells randomly infiltrate the stroma singly, in tiny clusters and cords. Some cells are present within endothelial-lined spaces.
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I will really appreciate for those who could help me understand it because I really care for my mother's health.
I wanted to know if she really needs to undergo mastectomy.
Right now, we couldn't decide what to do yet.
you can mail me at this address for those who wanted to help me:
jinkz_013***@****
thank you
this is my mom's laboratory result after she undergone a lumpectomy and i wanted to understand it clearly.
Pathologic Diagnosis:
Excision Biopsy, Breast mass, Right:
-INVASIVE DUCTAL CARCINOMA
gross description:
the specimen consists of an irregulary-shaped, brown-yellow firm mass measuring 3.7 x 2.7 x 1.7 cm. Sections disclose gray-white mottled cut-surface with an ii-defined, opaque, white-brown central area measuring 1.5 cm in widest dia. Rep.
microscopic description:
Microsections of the breast mass disclose dilated ducts solidly filled with neoplastic ductal cells having large, ovoid pleomorphic nuclei and moderate, eosinophilic, polygonal cytoplasm. These cells randomly infiltrate the stroma singly, in tiny clusters and cords. Some cells are present within endothelial-lined spaces.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I will really appreciate for those who could help me understand it because I really care for my mother's health.
I wanted to know if she really needs to undergo mastectomy.
Right now, we couldn't decide what to do yet.
you can mail me at this address for those who wanted to help me:
jinkz_013***@****
thank you
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How is your mother doing now? What has her oncologist advised?
The prognosis of invasive ductal carcinoma depends on its histological subtype. Mucinous, papillary, cribriform, and tubular carcinomas have longer survival, and lower recurrence rates. The prognosis of the most common form of IDC, called "IDC Not Otherwise Specified", is intermediate. Finally, some rare forms of breast cancer (e.g. sarcomatoid carcinoma, inflammatory carcinoma) have a poor prognosis.
Regardless of the histological subtype, the prognosis of IDC depends also on its staging, histological grade, expression of hormone receptors and of oncogenes like HER2/neu.
Treatment of IDC is surgery to remove the main tumour mass and to sample the lymph nodes in the axilla. The stage of the tumor is ascertained after this first surgery. Adjuvant therapy usually includes chemotherapy, radiotherapy, hormonal therapy (e.g. Tamoxifen) and targeted therapy (e.g. Trastuzumab). More surgery is occasionally needed to complete the removal of the initial tumor or to remove recurrences.
Let us know what the oncologist and breast specialist advise in your mother's case.
Post us if you have any other doubts.
Regards.