recurrence

My friens wife 46 years old  pre - menopausal female known treated case of right breast cancer in 2002 gone for Modified Radical Mastectomy with three cycles of Chemo therapy (FEC) pre-operative & one cycle  of Chemo therapy post operative ( FEC)  and Four cycles of Taxotere with Herceptin 4 doses followed by Radiation. This was followed by Tab. Tamoxifen 20mg (1) for five years and Tab. Femora for further one year.

SheI had disease free period for six years.

She had symptoms of mild pain in chest therefore she has undergone PET-CT Scan to see the disease status. Report of PET-CT revealed Metabolically active multiple skeletal metastases. CT Scan revealed no visceral involvement at all. Right sided  minimal pleural effusion is seen ( Query H/O history of AKT after Chemo for skin lesions )

Please advice further line of treatment with recent studies and follow-ups based on following histopath reports after MRC :-

1)Infiltrating duct carcinoma , grade 3 ( Nottingham modification of bloom Richardson grading system)
- Associated DCIS with comedonecrosis, intermediate nuclear grade
2) Nipple and surgical margins- free
3) Axillary lymph node metastasis present (6/16)

With Her2/neu oncoprotein positive
Intensity  2+
% Her2 / neu  positive 80

[japdip]

I believe you received a response to this same post by one the the Physicians who answers posts on this Forum. I also read the report and the only mention of metastises was to the bone which can be treated by rather simple methods. She should of course follow the recommendation of her Oncologist regarding this matter.