Atypical tumor markers

Do you know the original tumor or description of a tumor in the fatty tissue of the abdomen with:

Positive Cytokeratin 7
Positive 20
Negative CDX2

Thanks

[Fernando Roque, MD]

Hi. A positive Cytokeratin 7 and Cytokeratin 20 would indicate any of the following tumors:  mucinous ovarian carcinoma, bladder cancer, stomach or pancreatic adenocarcinomas, or bile duct cancer (cholangiocarcinoma).  CDX2 is a marker for tumors originating from the duodenum or the colon and rectum, so a negative CDX2 rules out a duodenal or colorectal origin of that abdominal tumor.