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Doctor: Please let me know as soon as possible - desperate

Dear Doctor:
Before, I have received your kind answer of which I learned that there is noting to be concerned of as far as HIV-2 in my case after 25 years from one sexual contact with white female prostitute in the U.S.A. and after two separate lab based negative results on HIV-1 Elisa done 21 years ago and- 3 years from such contact (in 1988 & 1989). I am healthy. However, anxiety, quite often is a nasty thing and does not want to listen to a reason or logics. That fear, kind of blurs you actual inner vision and deprives you of some necessary distance to that particular issue. The more you resist the more anxious you become. Sort of like a vicious circle that you are in. So, I need to face it and test on HIV-1/HIV-2 combo Elisa or ruin my life. However, I am so afraid of false positive results. I heard that HIV-2 does not have any approved confirmatory Western Blot test, I think increasing false positive to compare it with HIV-1??
Therefore, let me ask you to ALL my questions:

1. What are the chances of such scenario being false positive/ inconclusive in my case (no recent vaccines, no known disease, none of exposures)? – With Western Blot for HIV-1 there is more assurance than HIV-2 before it leaves the lab, isn't it? Did you have any cases like that, often?
2. How any possible false positive (on HIV-2 with that HIV-1/HIV-2 combo) would usually be confirmed by lab before I get my results, or perhaps they will just leave me with some inconclusive result to worry?
3. If they would, so what test/s I could follow up with to resolve it immediately?
4. Could PEP (rabies vaccination and immune globulin) received almost 3 years ago due to dog accident, cause the test now to be false positive?
5. Would you say Doctor that with 25 years I would be somewhere on the top when considering long incubation for HIV-2?
6. Could HIV-1 tests in 1989 I had (I think 2-nd gen.)  partly cross-react with HIV-2 after 3 years, or no way? - Respectfully yours - Rysiek.

2 Responses
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300980 tn?1194929400
MEDICAL PROFESSIONAL
Welcome back to our Forum. In preparing to answer your questions I reviewed your previous interactions both on our Forum and on the International HIV Forum.  Your testing would have detected HIV-2 infection.  Having done so, I can say that your fears have no basis in fact and that you need to figure out how to move beyond your fears, even if it requires the help of a mental health professional.  I will go straight to your specific questions but the sentence before this one provides the most important advice I can give you.

1.  Too close to zero to give any other answer than zero- no risk.
2.  All false positives would be ruled out with confirmatory testing.  The is no reason for further testing
3.  See above
4.  No, rabies vaccine would not give you a false positive test
5.  25 years is far beyond the time needed to detect HIV or any sort.
6.  Yes, tests in 89 would have almost certainly detected HIV-2.

Bottom line.  Your fears are totally inappropriate. You need to move beyond your fear of HIV.  There will be no further answers. Further questions will be deleted without comment.  EWH
Helpful - 1
Avatar universal
Thank you Dr. Hook for your kind clarification to my primary question/s. I am sure it will be helpful and beneficial even as it is.

Kind regards,
Rysiek.
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