Dear Doctor:
Before, I have received your kind answer of which I learned that there is noting to be concerned of as far as HIV-2 in my case after 25 years from one sexual contact with white female prostitute in the U.S.A. and after two separate lab based negative results on HIV-1 Elisa done 21 years ago and- 3 years from such contact (in 1988 & 1989). I am healthy. However, anxiety, quite often is a nasty thing and does not want to listen to a reason or logics. That fear, kind of blurs you actual inner vision and deprives you of some necessary distance to that particular issue. The more you resist the more anxious you become. Sort of like a vicious circle that you are in. So, I need to face it and test on HIV-1/HIV-2 combo Elisa or ruin my life. However, I am so afraid of false positive results. I heard that HIV-2 does not have any approved confirmatory Western Blot test, I think increasing false positive to compare it with HIV-1??
Therefore, let me ask you to ALL my questions:
1. What are the chances of such scenario being false positive/ inconclusive in my case (no recent vaccines, no known disease, none of exposures)? – With Western Blot for HIV-1 there is more assurance than HIV-2 before it leaves the lab, isn't it? Did you have any cases like that, often?
2. How any possible false positive (on HIV-2 with that HIV-1/HIV-2 combo) would usually be confirmed by lab before I get my results, or perhaps they will just leave me with some inconclusive result to worry?
3. If they would, so what test/s I could follow up with to resolve it immediately?
4. Could PEP (rabies vaccination and immune globulin) received almost 3 years ago due to dog accident, cause the test now to be false positive?
5. Would you say Doctor that with 25 years I would be somewhere on the top when considering long incubation for HIV-2?
6. Could HIV-1 tests in 1989 I had (I think 2-nd gen.) partly cross-react with HIV-2 after 3 years, or no way? - Respectfully yours - Rysiek.