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OraQuick Home Oral Swab Test

Good Morning Dr. Handsfield and Dr. Hook,

I have a few questions about the OraQuick Home Mouth Swab test. From what the information from the site it says:

"Oral fluid HIV tests are very accurate. In studies, the OraQuick oral fluid test detected 91.7 percent of people who were infected with HIV, and 99.9 percent of people who were not infected with HIV."

That seems really not very accurate! I've done a couple of them over the last year and now I am thinking maybe they aren't all that accurate to base my health on. So a few questions for you two.

#1. Does this mean it has false negatives 8.3% of the time?
#2. Does this accuracy get better over time?
#3. I tested with two of these tests 3 years after a potential exposure, would that time frame make it any more accurate? And if so, how much more accurate do you think it would make it?
#4. Would you in your practice relay on this test? Would you recommend this test?
#5 Would using this test to confirm a negative blood test from lab error, or any other type of error or mistake that could happen be accurate and reliable to do? And assure that I am 100% negative, no questions asked, no ifs, buts or what-ifs?

Thanks for taking the time to answer my questions! I hope you Doctors are having a good weekend! It's 4 degrees here so I am trying to not get Hypothermia!!! :-) Hopefully with your knowledge I can forget HIV and worry about more important things in life. Like staying warm!!!!

Best to you both!
6 Responses
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300980 tn?1194929400
MEDICAL PROFESSIONAL
1. What is the percentage of false negatives on OraQuick At-Home Drugstore bought test if taken 5 and half to 6 years after exposure?
Virtually zero.

2. Would taking two of them make the percentage even lower?
Yes, doing the test twice would assure you that the test had not been done incorrectly.

Take care. Please do not worry.  EWH
Helpful - 0
Avatar universal
Dr. Hook,

Sorry typo and forgot to address it to you. Last question. Guaranteed. Than I am moving on to greener pastures!

1. What is the percentage of false negatives on OraQuick At-Home Drugstore bought test if taken 5 and half to 6 years after exposure?

2. Would taking two of them make the percentage even lower?

Thank you for the time you have given up to answer my annoying questions. You are a true expert and a saint for what you offer us. You and Dr. HHH are some of the last few remaining true medical heroes.

Goodnight and take care!
Helpful - 0
Avatar universal
Dr. Hook,

Last question. Guaranteed. Than I am moving on to greener pastures!

1. What is the percentage of false negatives after the 3 month mark on the OraQuick At-Home Drugstore bought test?

2. Would taking two of them make the percentage even lower?

Thank you for the time you have given up to answer my annoying questions. You are a true expert and a saint for what you offer us. You and Dr. HHH are some of the last few remaining true medical heroes.

Goodnight and take care!
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL
I understand which test you are talking about.  

Between your earlier lab test and your two OraQuick tests, you can be completely confident that you do not have HIV. Further testing of any sort is a waste of time and resources unless you have further worrisome exposures.  

Take care.  EWH
Helpful - 0
Avatar universal
Thank you Dr. Hook for your answer. Just to be clear I am talking about the OraQuick Home test that you buy at your local CVS or Walgreens. I got those stats from the web site at:

http://www.oraquick.com/FAQs under the "How accurate is HIV testing using oral fluid?" tab.


Sorry question #5 wasn't clear.

What I meant was. Earlier I had a HIV antibody blood test that was negative. But after the test I started to worry maybe someone made a mistake like the lab or doctor. So I than did the two OraQuick at home tests that were both negative. Would the two OraQuick at home tests confirm the results from my lab test are accurate and no mistakes were made? And no reason to worry and that my results are 100% accurate?

Thank you.
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL
Welcome to the Forum.  I am not sure what site you are getting the information that you mention from.  The figures for sensitivity seem low.  In getting approved for HIV antibody detection this test needed to perform as well as lab based tests, and it does.  Soon after infection (in the first 8-12 weeks) the OraQuick is slightly less sensitive than lab based tests but after 12 weeks it works as well as any other test, detecting virtually all infections.  If you have had two successive next tests, my advice would be to believe the results and not worry further.

As for your specific questions:
1.  That is what the figure means but, as I said, the OraQuick does not miss that many infections.
2.  After 12 weeks these tests are as good as any other antibody detection tests.
3.  Your results are accurate.  I urge you to believe them.  Further testing will not show different results.
4.  Yes, this is.a good test and we have used it in settings where we cannot use blood tests.
5.  Not sure I follow this question.  That said, again, I urge to to believe the results.  EWH
Helpful - 0

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