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Peace of mind

Dear Doctors,

I had unprotected sex with escort last year on October, after 10 months from this activity I did the Combo test ag/ab and came Negative. I ask the doctor is this conclusive and the answer was No !! I told him why?

His answer was the following :

90% of the infected people their tests will turn positive after 2-3 months from the exposure.
7% of the infected people they need extra 3 months , so they need to wait 6 months.
3% of the infected people Never will develop antibodies and there are documented cases!

Am so worried and cannot have any sex with my wife.

If this percentages are correct that mean 30 people out of 1000 their test will show negative but they are Positive.

My questions:

1- I need your comment doctor for the above , please.
2- let's assume my body didn't produce any antibodies , what I understand that the p24 antigen after 4-5 weeks will disappears ,  that's mean my test which I did it after 10 months from the Risk it's false negative , it's possible ? Why ?

3- for peace of mind , can the Pcr test help me to give me conclusive and definitive result?
4- is there any combination / tests you recommend doctor to give 100 % accurate result especially after 10 months?

5 -  I found some examples for some people who their tests turn positive after one year , what the reasons doctor?

Thanks an best regards,
3 Responses
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239123 tn?1267647614
MEDICAL PROFESSIONAL
I stand by my original reply.  To my knowledge, there have been few if any reported cases of people with HIV having negative results on all the HIV tests you have had. Even if your doctor is correct, i.e. if rare persons don't produce detectable antibody, the p24 part of the test would be positive.

1) No.  See my original reply.

2) PCR is primarily used to evaluate the severity of infection in people already known to have HIV, and to measure the effectiveness of treatment.  It is sometimes used within 3-4 weeks after exposure, when there is a strong suspicion HIV before either antibody or p24 become positive.  There is no need and no point to using PCR in people with the negative test results you have had.

3) There is no chance you have HIV and you should be continuing unprotected sex with your wife.   You cannot infect her with something you do not have.

That will end this thread.  Believe the science and move on with your life.
Helpful - 0
Avatar universal
Dear dr,

Thank you for your response. Much appreciated.

Yesterday , i went to the clinic and ask the doctor to not mention this kind of information because it's depend on old tests. He start laughing and later told me that theoretically it's Possible that the body will not develop the antibodies ,so how the modern tests will detect the antibodies!

I went back home and fully worried and I don't know what to do.

Your comments doctor for the above?

Below my last questions :

1- it's possible the antigens will disappear without producing antibodies?
2- in which cases the Pcr test is necessary?
3 - your final recommendation for my case and can I have sex with my wife without any doubt that I got HIV 1% ?

Thanks and best regards,
Helpful - 0
239123 tn?1267647614
MEDICAL PROFESSIONAL
Welcome to the forum.  Thanks for your question.

First, I'll say that in the US and other industrialized countries, HIV is believed to be rare (under 1 chance in 1,000) in most escorts, i.e. upscale/expensive female sex workers by appointment.  And even if yours had HIV, the average transmission risk per unprotected vaginal sex exposure is under 1 in 1,000.  So even without testing, the odds you caught HIV was in the range of 1 in a million.  And even if your doctor were correct that your negative test result was "only" 90% reliable, that result drops your risk down to 1 chance in 10 million.  So even if I agreed with your doctor's statistics (see below), I would advise you not to be worried and that no further testing is necessary.

1) As implied above, your doctor's views on HIV testing are atypical and almost certainly wrong.  Perhaps he is referring to the older HIV antibody tests no longer used.  The stand-alone antibody tests in current use are virtually 100% reliable after 6-8 weeks, and the combination of negative antibody plus p24 antigen 100% reliable any time after 4 weeks.  (See http://www.medhelp.org/posts/show/1704700)

2) If you didn't produce antibodies but had HIV, the p24 component of the test would be positive.  It's the antibody that clears p24 from the blood; without antibody, p24 ould persist.  That's why the test is 100% reliable:  after 4 weeks, either antibody or p24 is always present in HIV infected people.

3) I recommend against PCR testing.  It's expensive and unecessary.

4) You've already had 100% reliable test results.

5) Such delayed positive results are for antibody only, and have probably not occurred for 15+ years, since routine use of modern tests.

Bottom line:  You were at very low risk for HIV to start and your test results prove conclusively you were not infected.  You need not be at all worried and do not need further testing.

Best regards-- HHH, MD
Helpful - 0

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