Doi have any infection in my body...............

[vvvm]

Hi doc, Currently i have swollen lymph nodes in neck and arm pits, mouth burning like anything all the time, apthous mouth ulcers inside cheeks, lymphadenitis, pain in b/l arm pits and in the scapular region, pectoral region.......no other symptoms............such as fever, headache, diarrhea, skin rash..........

My HSV 1 Ig G levels on 11/28/12 are 3.76...............and Hiv icma NEGATIVE;

ON 12/07/12 HIV RNA qualitative negative...........

On 02/15/13 HSv 1 IG g levels are 3.38 and HIV icma negative and Hiv rna QUALITATIVE TEST NEGATIVE;

On 07/03/13 HSV 1 IG g levels are 4.02 and HIV icma negative and HIV rna qualitative negative............

On 01/06/14 HSV 1 IG levels are 3.62 and HIV icma negative and HIV rna qualitative test negative..........

On 01/11/14 my CD4:CD8 profile ratio.................

Test                                                      Result                Flag               Reference Interval

Absolute Cd4 helper                         879 /ul                                          359-1519

% of cd4 pos. lymph                         31.4%                                           30.8% - 58.5%

Ab cd8 suppressor                              1204/ul                High                    109 - 897

%  cd8 pos. lymph                             43%                    High                     12 - 35.5%

CD4 : CD8 ratio                                 0.73                    Low                       0.92- 3.72

Other STD test results were negative.............

Why my cd4:cd8 ratio is low?

why my ab cd8 suppressor and cd8 pos lymph % is high?

I just want to know do i have any infection in my body that is life threatening, plz confirm it.........
Do I need to take any other lab tests to confirm that I am negative.........because, I am planning for another HIV 4th generation test..................plz let me know do I need it........

[Edward W Hook, MD]

Your tests prove that your problem is not a STI.  Beyond this is neither my area of expertise, nor the focus of this Forum.   It is now time to work with your doctors for other, non-STI causes.  EWH

[vvvm]

My STD test are negative, but still I have mouth burning, white coated toungue, lymphnode swelling, and mouth ulcer on inside my cheek on left side, I did all the std test on regular basis.....but still why have these symptoms..............

[Edward W Hook, MD]

Welcome to our Forum.  I'm not sure why you are worried about STIs or HIV but he test results you describe clearly prove that you have not recently acquired HIV and that you probably have HSV-1, as do over 60% of normal adults (typically resulting from oral infection acquired during childhood).  

The CD4/CD8 ration is outdated and no longer used to evaluate person with HIV ad has NO role in evaluating risk for infection in others who do not have HIV.  Your CD8 cell count is high and your CD4 lymphocyte count is normal.  In persons with HIV, the CD4 count is low because of the infection (the virus selectively destroys CD4 cells) and that, in turn, makes the ratio of CD4 to CD8 cells also low.  In normal people both CD4 and CD8 counts fluctuate a great deal normally.  

In answer to your specific questions:
Why my cd4:cd8 ratio is low?
See above.  Getting a CD4/CD8 ratio is a waste of money for person who do not have HIV and you do not have HIV.

why my ab cd8 suppressor and cd8 pos lymph % is high?
See above. There are any number of reasons which could explain this. it is not something to worry about.

I hope these comments are helpful to you.  Are you ordering these tests yourself or is your doctor doing this.  In either instance, although I have not taken a full history from you, I see no reason for doing these tests or to worry further about HIV from past exposures. EWH