drug interaction

[Bob141]

how does dexlansoprazole interact with plavix

[ed34]

There are many strange things which seem to occur with plavix, but more research is required. Two friends of mine are studying to be Pharmacists and they have been told for example that Plavix has very little effect, or none at all, on the female Gender. Nobody knows why.

[Flycaster305]

I've followed this research, and from what I've learned the drug interaction of Plavix and PPI's (proton pump inhibitors) is not not that strong.  I doubted the report from the start as I took Plavix and PPI's and my blood was as thin as tea, I bruised very, very easily, and the blood tests to determine my clotting factor wasn't changed by taking the two drugs.  

[ed34]

Plavix (Clopidogrel)  requires cytochrome P450 enzymes produced in the Liver, and specifically cytochrome P450 2C19. Some proton pump inhibitors (e.g. omeprazole) can reduce these enzymes making Plavix far less effective.