Just to let you all know I went in to the Er Monday with the intention of getting these chest pains checked out and sent right back home. The decided to do an cat-scan angio-gram and found 80 % blockage of my left descending coronary artery and other blockages. Went to the cath lab with my cardiologist and a catheter was placed into the femoral artery in my groin and several stents were placed successfully.
If I had not stopped taking Metoprolol Iprobably would be dead as the drug was masking my symptoms. Feeling better now
Like Jerry above, I too have taken as much as 200mg of Metoprolol daily, and reducing it produced no ill effects. When I had my electrophysiology study, I had to discontinue it completely. I saw no effect by abruptly stopping it, and had no rebound effect either. 25mg twice a day is a pretty small dose. I'm on 75mg per day as a maintenance dose and suffer no I'll effects except it takes a little longer to get my heart up to workout speed. I'm 63 years old and a T2 diabetic controlled by diet only.
I have been on beta blockers including Toprolol, Metoprolol and Atenolol which is what I am now using. All gave/give me the list of side effects you mention, but I take a larger dose, 24 mg twice a day on Atenolol. I also take a calcium channel blocker... all because of atrial fibrillation, which I have permanent.
I have undergone significant shifts in dose levels, as high as 100 mg twice a day and have never developed any of the "withdrawal" symptoms you list. I agree it seems unlikely that withdrawal symptoms would not develop for the first 1.5 week, but I have nothing but personal experience to base my agreement on.
Perhaps someone with a similar experience can shed some light.