Everyone reacts differently. Many people are able to work, go to school and fare considerably well. Others have a hard time. I was mostly bedridden during my 32 weeks of treatment, but very quickly felt better after stopping.
Have a look at the health pages, there are a few pages with suggestions for tx.
http://www.medhelp.org/health_pages/list?cid=65
Wishing you good luck!
Since you are already on the thin side, be sure to keep up your nutrition during treatment. You might have to work at that -- which is something I had to do too.
Big hug to you for beating breast CA...now go beat that HCV!!