Aa
Why do we usually only contract one gentype of Hep C?
I always wonder why people who have been in high-risk situations,( such as a blood transfusion before 1991, or who were not careful, when using I.V. drugs) only tend to get one genotype of Hep C? I have heard of people who have both Hep B and C, but I have never heard of anybody with both genotype 1 and 2, or 2 and 3, or 1a 1b, etc, for instance~ Does anybody know, or care to speculate? Speculations are fine, as none of us here are Doctors (that I know of at least), and this is...after all,,the social side:)
Best Answer
Have an Answer?
You are reading content posted in the Hepatitis Social Community
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Abstract:
The frequency of hepatitis C virus (HCV) superinfection with a divergent viral strain was determined in a cohort of recently infected young injection drug users (IDUs) with an HCV incidence rate of 25%. HCV was amplified, by use of polymerase chain reaction (PCR), from plasma samples collected from 25 HCV-infected individuals over an average period of 12 months, and their viral sequences were compared. Phylogenetic analysis identified 5 IDUs with superinfection (20%) occurring after seroconversion: 2 IDUs were superinfected with different HCV genotypes, and 3 were superinfected with divergent strains of the same genotype. The superinfecting strains were not detected as minority variants (<0.5%) in the initial plasma HCV quasi species. Extensive measures were taken to exclude PCR contamination and mix-up of samples, and superinfection results were concordant at 2 HCV genetic loci. HCV superinfection in IDUs, both intra- and intergenotype, is therefore a frequent event, with an incidence rate similar to that of de novo infections. These results suggest that no cross-protecting immunity develops during the first year of chronic infection with HCV.
http://www.jstor.org/discover/10.2307/30078061?uid=2129&uid=2&uid=70&uid=4&sid=21102589937301