Aa
y has no one used milk thistle it worked for me
y not milk thistle
BTW, milk thistle virgocharm is for real. I got a pm, ending with the words: marcia educate your mind. dig and dig and dig.
In a way the pm was quite naively explaining how good he/she feels from all the natural things, with no data showing improvement results or biopsies to account for the great progress since dxed 7 months ago. The pm was quite unpleasant , verging on rude and I actually feel like posting it, but don't know if it is ethical to do it. I am not used to people speaking to me in that tone and the ignorance really pi$$ed me off.
Marcia
In a way the pm was quite naively explaining how good he/she feels from all the natural things, with no data showing improvement results or biopsies to account for the great progress since dxed 7 months ago. The pm was quite unpleasant , verging on rude and I actually feel like posting it, but don't know if it is ethical to do it. I am not used to people speaking to me in that tone and the ignorance really pi$$ed me off.
Marcia
Yay, you found it! I still don't know what aggregation means. I must admit that I don't understand most of what they are saying. But it seems to be having a positive effect, if I understand correctly. I can see that I have a lot of holes in my English vocabulary. It would be really nice, if you could help me out.
Thanks, Marcia
Thanks, Marcia
Cocoa flavanols and platelet and leukocyte function: recent in vitro and ex vivo studies in healthy adults.
Heptinstall S, May J, Fox S, Kwik-Uribe C, Zhao L.
Cardiovascular Medicine, University of Nottingham, UK. s.***@****
There is growing interest in possible beneficial effects of specific dietary components on cardiovascular health. Platelets and leukocytes contribute to arterial thrombosis and to inflammatory processes. Previous studies performed in vitro have demonstrated inhibition of platelet function by (-)-epicatechin and (+)-catechin, flavan-3-ols (flavanols) that are present in several foods including some cocoas. Also, some modest inhibition of platelet function has been observed ex vivo after the consumption of flavanol-containing cocoa products by healthy adults. So far there are no reports of effects of cocoa flavanols on leukocytes. This paper summarizes 2 recent investigations. The first was a study of the effects of cocoa flavanols on platelet and leukocyte function in vitro. The second was a study of the effects of consumption of a flavanol-rich cocoa beverage by healthy adults on platelet and leukocyte function ex vivo. Measurements were made of platelet aggregation, platelet-monocyte conjugate formation (P/M), platelet-neutrophil conjugate formation (P/N), platelet activation (CD62P on monocytes and neutrophils), and leukocyte activation (CD11b on monocytes and neutrophils) in response to collagen and/or arachidonic acid. In the in vitro study several cocoa flavanols and their metabolites were shown to inhibit platelet aggregation, P/M, P/N, and platelet activation. Their effects were similar to those of aspirin and the effects of a cocoa flavanol and aspirin did not seem to be additive. There was also inhibition of monocyte and neutrophil activation by flavanols, but this was not replicated by aspirin. 4'-O-methyl-epicatechin, 1 of the known metabolites of the cocoa flavanol (-)-epicatechin, was consistently effective as an inhibitor of platelet and leukocyte activation. The consumption of a flavanol-rich cocoa beverage also resulted in significant inhibition of platelet aggregation, P/M and P/N, and platelet activation induced by collagen. The inhibitory effects were related to their flavanol content. There was also inhibition of monocyte and neutrophil activation, but here it was concluded that cocoa constituents other than flavanols may contribute to the inhibition that was observed. It can be concluded that cocoa flavanols, their metabolites and possibly other cocoa constituents can modulate the activity of platelets and leukocytes in vitro and ex vivo. The research suggests that the consumption of certain cocoa products may provide a dietary approach to maintaining or improving cardiovascular health.
http://www.ncbi.nlm.nih.gov/pubmed/16794458
Heptinstall S, May J, Fox S, Kwik-Uribe C, Zhao L.
Cardiovascular Medicine, University of Nottingham, UK. s.***@****
There is growing interest in possible beneficial effects of specific dietary components on cardiovascular health. Platelets and leukocytes contribute to arterial thrombosis and to inflammatory processes. Previous studies performed in vitro have demonstrated inhibition of platelet function by (-)-epicatechin and (+)-catechin, flavan-3-ols (flavanols) that are present in several foods including some cocoas. Also, some modest inhibition of platelet function has been observed ex vivo after the consumption of flavanol-containing cocoa products by healthy adults. So far there are no reports of effects of cocoa flavanols on leukocytes. This paper summarizes 2 recent investigations. The first was a study of the effects of cocoa flavanols on platelet and leukocyte function in vitro. The second was a study of the effects of consumption of a flavanol-rich cocoa beverage by healthy adults on platelet and leukocyte function ex vivo. Measurements were made of platelet aggregation, platelet-monocyte conjugate formation (P/M), platelet-neutrophil conjugate formation (P/N), platelet activation (CD62P on monocytes and neutrophils), and leukocyte activation (CD11b on monocytes and neutrophils) in response to collagen and/or arachidonic acid. In the in vitro study several cocoa flavanols and their metabolites were shown to inhibit platelet aggregation, P/M, P/N, and platelet activation. Their effects were similar to those of aspirin and the effects of a cocoa flavanol and aspirin did not seem to be additive. There was also inhibition of monocyte and neutrophil activation by flavanols, but this was not replicated by aspirin. 4'-O-methyl-epicatechin, 1 of the known metabolites of the cocoa flavanol (-)-epicatechin, was consistently effective as an inhibitor of platelet and leukocyte activation. The consumption of a flavanol-rich cocoa beverage also resulted in significant inhibition of platelet aggregation, P/M and P/N, and platelet activation induced by collagen. The inhibitory effects were related to their flavanol content. There was also inhibition of monocyte and neutrophil activation, but here it was concluded that cocoa constituents other than flavanols may contribute to the inhibition that was observed. It can be concluded that cocoa flavanols, their metabolites and possibly other cocoa constituents can modulate the activity of platelets and leukocytes in vitro and ex vivo. The research suggests that the consumption of certain cocoa products may provide a dietary approach to maintaining or improving cardiovascular health.
http://www.ncbi.nlm.nih.gov/pubmed/16794458
You sure had me laughing, when I first saw the post. What a good distraction. Cocoa, chocolate! I actually think that the first post is another imposter... I mean milk thistle ... again? And I don't think the person is coming back for any answers. Just my opinion, was actually suspecting it from the beginning.
But what about the platelet aggregation??? What does that mean? Maybe we're on to something new!
Marcia
But what about the platelet aggregation??? What does that mean? Maybe we're on to something new!
Marcia
I just found the article interesting and since milk thistle is such an over worked subject I just stuck this cocoa thing in here. I was going to post regarding Milk of Magnesia but this seemed a better choice.
Relevance? Well, since diabetes is associated with HCV maybe that's a plausible connection..... albeit a trifle tenuous.
Mike
Relevance? Well, since diabetes is associated with HCV maybe that's a plausible connection..... albeit a trifle tenuous.
Mike
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