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After complaining to my primaryPrimary amyloidosis Primary biliary cirrhosis Primary hyperparathyroidism Primary insomnia Primary lymphoma of the brain care MD about constant muscle twitching in the calves of my legs that has persisted for almost a year and then some muscle weaknessWeakness she sent me to a Neurologist. He performed an EMG/nerve conduction velocity which indicated moderate to severe demylination in both calves and my right arm. I am now having severe cramping in my calves and I am taking 3200mg of Neurontin a day with littleLittle noses decongestant Little tummys or no help. All test for an underlying cause have been negative except for a slight elevation in protien in my spinal fluid. I am now awaiting a nerveNerve biopsy Nerve conduction velocity/muscle biopsy before the Neurologist will begin treatment with steroids. How can I manage the pain associated with the cramping? Is this cramping normalNormal saline flush? The Neurontin is of little help. My hot tub does offer some relief but only for a short time. HELP