CP from antiphopholipid syndrome

My wife has SLE and antiphospholipid syndrome.  During the delivery fetal heart rate problems were recognized and an emergency c section was done.  Our baby was 5.5 pounds, and my wife was 39 weeks pregnant.  our son is now 2, and was diagnosed with spaztic quadraplegic cerebral palzy that the doctors says is from y wife's antiphospholipid syndrome.  The doctors say my wife's antiphopholipid syndrome caused the antibodies to go to the baby in the womb and caused the CP.  Can this happne, and if so is there any articles on the subject.

[Abhijeet Deshmukh, MD]

Hello.

I have found just one reference which mentions the relationship. I will paste some part of it. You can follow the link and read the rest.

The article is a study by Zh Nevrol Psikhiatr Im S S Korsakova, published in 2006, an is titled "A pathogenetic model of cerebral palsy in children born to mothers with antiphospholipid syndrome". It is a Russian article.

".......Thirty-two children with cerebral palsy born to mothers with clinical signs of APS have been studied. The basic clinical feature of cerebral palsy in children was the prevalence of the double hemiplegic form, the absence of severe cognitive disorders, global muscular hypotrophy, rapid contracture formation and a tendency to frequent respiratory diseases...."

"........(2) transplacental passage of antiphospholipid antibodies from a mother to a child;....."

Regards

[Abhijeet Deshmukh, MD]

Here's the link. It is lengthy. Please make sure you have copied the whole link. Triple click on the link will select the whole link. Then you can right click and copy.

http://www.ncbi.nlm.nih.gov/pubmed/16921719?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Regards