MS AND ELEVATED (ABSOLUTE) LYMPHOCYTES

I am an MS patient - diagnosed approximately 12 years ago.  I am currently on Copaxone, Depakote, Neurontin, for the MS; Evista for osteoporosis, Tenormin, (as a beta blocker),for Migrane (migraine) headache, Cinestin - an estrogen replacement (I had a complete Hysterectomy in 1991), Vesicare and Oxytrol for my neurogenic bladder and Tylenol with codine for acute pain.  I recently had blood work and my WBC was slightly elevated at 11, RBC, Hemoglobin, and Hematocrit were slightly low and my lymphocytes were above 5000, (high normal is 3900).  I have been in acute pain, (legs and arms), and have been suffering with extreme fatigue for about 3 months now.  Is there a relationship between an MS flare and a high Lymphocyte count?  Has any one else had a similar situation?  I have contacted my neurologist to get a copy of my previous blood work for comparison, (the recent blood work was not ordered by him).  Any assistance any one can give would be greatly appreciated. I am a bit nervious that something else is going on.

LAS

[wingnut19]

Hi

I am very interested in getting an answer to this question as well....I am going to bump it to the top and hopefully a doctor will see it..

:)

T.

[Nerve_Wrecked]

I too am very very interested in this. I have multiple neurological type symptoms, with no known cause, except "probable early MS", and have had chronic lymphocytosis ( usually around 6000 or 6100) for almost 3 years (if not longer).

Christine
(un-dx)

[wingnut19]

bump

[jwslas]

Thankx for the bump.

Las

[ShakinThingzUp]

I read something today in my own research, and thought of this post..... came back to post it here - may mean nothing - but may be of interest to some of you.

Do a search for Devic's syndrome.  (Neuromyelitis optica - NMO)

The research I read indicates it is slightly different than or a type of MS - one of the differences is heightened leukocytes.

God bless each of you.
Amy

[jwslas]

Thankx for the info.  Googled Devic's Syndrome - while I don't think I meet all of the criterial - it is nice to know that a blood test may be all that's required to rule Devic's in or out.

Will talk to my neuro at my next appointment.

LAS

[Nerve_Wrecked]

Bumping this up again.

PS. Devic's doesn't fit for me since I haven't had Optic Neuritis, but thanks for the suggestion. I am always thrilled to get new ideas and thoughts!


Christine
(un-dx)

[wingnut19]

bump

[Nerve_Wrecked]

Bump.....I wish someone would provide some thoughts about this, apparently several people want to know.

[Nerve_Wrecked]

Bumping it up again....just incase.

[wingnut19]

Bumping again for doctor's opinion please!!  :)

[wingnut19]

bumping for the 2387923702373987587857th time   :)

[wingnut19]

Somebody, anybody????

[ShakinThingzUp]

Still no doctors attention, but try reading this article while you wait.... (and I figured this might keep it at the top a bit longer by bumping it up).


http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1809442

[wingnut19]

Thanks!

:)

[ShakinThingzUp]

I read more of the article after posting - I realize this is simply research at this point, but it appears to indicate that someone with MS who has raised Lymphocytes might indicate that they ALSO have Chronic Fatigue Syndrome?????? due to the statistics of people with Chronic Fatigue Syndrome who had raised Lymphocytes????

This is not a scientific answer of course, just a conclusion drawn from what their studies suggest.  Of course, there are also plenty of sites that mention increase lymphocytes as being related to Leukemia....

God Bless!
Amy