Undiagnosable symptoms

[michelle123456789]

First off thanks for your time on my question. I am a 39 year old woman who has generally good health. This last November i started having a mild vibrating feeling behind my knee and to my left foot while at rest which has since subsided. Since them I have what you would call twitching to every part of my body including feet, legs, abdomen, hands, arms, neck, and face and prickling pins and needles sensations to hands and feet which also subside with movement. Most of the time the twitches i experience are single fire twitches that feel like a painless rubberband being snapped under my skin at other times (much less often) they resemble an eye twitch which subside also when i move the extremity in question. I have seen a neurologist and had two WNL neuro exams, normal MRI of brain and c-spine, normal nerve conduction studies, and a 3 needle emg to left shoulder, right calf, and right hand which was all normal as well (no fasiculations seen)...no muscle wasting or loss of strength seen, however I feel as if I have low energy but I may be able to attribute that to the stress of my current situation.

Labs I have had drawn are b12-340, ferriton-58, thyroid 0.47, potassium, calcium,
magnesium,sodium, and cpk all normal range

[Londres70]

Are your thyroid levels off?  I think I stated in a previous post to have your levels checked.  Sounds like the primary problem is your thyroid.  A thyroid problem cause so many other problems including b12 levels.  

What is your physician's plan of action to manage this?  

[michelle123456789]

Well, i went to my np and discussed my thyroid levels with her and she palpated my throat and actually felt my gland, she said that usually you should not be able to feel it. So she sent me for an ultrasound and sure enough there was a nodule found. So would it be reasonable to say that maybe this nodule is randomly shooting out excess thyroid or at least impairing the gland function? Thanks guys, feeling not so alone cuz i found you to help me along the way!! Btw, no better yet with the injections  

MIchelle

[Londres70]

Keep us posted.

[michelle123456789]

Well, started the b12 injections today, was given 1000mcg once weekly, so we will see if it helps. thanks for the advice!!

[Londres70]

I know just how you feel except I had a problem with anemia; felt like crap all the time.  I would recommend having your vitamin d level check and a TSH with T3 and T4.  

Try b12 injections as caregiver222 has mentioned.  

[Dr Sharma]

Hi there. Your ferritin levels are within normal range of 12-150 ng/mL, B12 levels also are in the normal limits of 200-900 pg/ml. thyroid hormone levels need to be checked with T3, T4, and TSH. These symptoms also need speculation for multiple sclerosis, despite so many investigations being normal. Consult a neurologist for investigating these. Multiple sclerosis is a chronic demyelinating neurological disorder where the disease phase is characterized by active phase and remissions. It has multiple symptoms and signs and is a diagnosis of exclusion. The symptoms of multiple sclerosis are loss of balance, muscle spasms, numbness in any area, problems with walking and coordination, tremors in one or more arms and legs. Bowel and bladder symptoms include frequency of micturition, urine leakage, eye symptoms like double vision uncontrollable rapid eye movements, facial pain, painful muscle spasms, tingling, burning in arms or legs, depression, dizziness, hearing loss, fatigue etc. You have many of these symptoms. The treatment is essentially limited to symptomatic therapy so the course of action would not change much whether MS has been diagnosed or not. Apart from clinical neurological examination, MRI shows MS as paler areas of demyelination, two different episodes of demyelination separated by one month in at least two different brain locations. Spinal tap is done and CSF electrophoresis reveals oligoclonal bands suggestive of immune activity, which is suggestive but not diagnostic of MS. Demyelinating neurons, transmit nerve signals slower than non-demyelinated ones and can be detected with EP tests. These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve responses in any one of these is not confirmatory of MS but can be used to complement diagnosis along with a neurological examination, medical history and an MRI and a spinal tap. Take care.

[michelle123456789]

Thanks so much for the input, I will get some b12 injections and see if they help at all. I tell ya, I feel terrible here. Once again thanks for taking the time for me, it is much appreciated!!

[caregiver222]

Londres70 has probably identified the problem. Although sublingual B12 has some effectiveness, you probably need, at least initially B12 injections.

[Londres70]

600 pg/ml is a good level in my opinion,  

[Londres70]

You are replying correctly.  A normal b12 level is 200-900 pg/ml.  Frequently, people experience symptoms when their b12 level is under 500.  

[michelle123456789]

I am not sure that I am replying right, Is there a specific way to do this?

[michelle123456789]

I started taking SL b12 a few weeks ago, little change is noted so far, no, have not had a D level checked yet. What do you feel a good level of b12 would be?

[michelle123456789]

I forgot to mention that the only medication I take is Ambien 5mg every night. Thanks so much again.

[Londres70]

Your b12 is low.  Are you taking supplements?  Injections?  Is your vitamin D level ok?