burning throat pain

For the past 7 months, I have experienced a variety of throat and esophageal pains and a feeling of a lump in the throat.  It started off as a feeling of something in my throat and has graduated to a burning, stabbing, piercing pain in my throat and esophagus.  The only time I don't experience this pain is when I'm eating and lying down/sleeping.  I have had my throat scoped by 2 ENTS, had 2 endoscopy procedures, an impedence pH procedure (24 hour), a swallowing test, bloodwork, my throat dilated and am having an MRI of the neck and throat today.  All of these tests came back showing I had a clean bill of health (no anemia, NERD, GERD, thyroid problems, tumors, etc.)  I have been to a total of 10 doctors and NO ONE knows what this is.  The pain is so severe that I went to the ER last night and they prescribed Percoset (sp?) which made me wired instead of tired.  It has been suggested that I go to Mayo but no one knows who I should go see.  It take prescriptions for anxiety/depression and a couple of the doctors said that I needed to alter my meds, which we have tried and tried and tried and none of it has given me ANY relief.  This all started after I started taking Cymbalta in March because my old antidepressant was no longer working.  In the past month, my doctor has gradually weaned me off of the Cymbalta and my throat felt better (but not gone) for 2 days and now the pain is right back where it was before.  I am desperate for any help!!

[Weesy68]

Insist that your doctor test your Vitamin levels, especially your Vitamin D, Vitamin B12, Ferritin levels (not just hematocrit or hemoglobin because Ferritin is the best test for iron deficiency).  These can cause your problems and should be checked.  Do not supplement without being tested because too much of these vitamins can be toxic, but I had similar symptoms as you and was extremely low on both Vitamin D and Ferritin which caused anemia.  I have just begun treatment so I do not know if it will clear but I am hopeful.  

[AngelaBedenbaugh]

I had these same symptoms many years ago and eventually lost my voice completely.  Please go to an ENT specializing in Laryngopharyngeal Reflux.  This doesn't show up on normal pH monitoring (because even normal pH can cause damage to vocal cords).  Have the ENT look at your vocal cords with a laryngoscope and make sure that you don't have any granulomas present (these can cause pain, tighness, globus sensation, etc.).  I've been on high-dose Proton pump inhibitors for the past 12 years for this and it's well managed, but I remember how awful it was at the time.  Good Luck!

http://heartburn.about.com/od/gastrictractdisorders/a/whatis_LPR.htm

[Yola1964]

I'm now going thru the same symptoms. I had an endoscopy procedure and after that my life is been miserable. I beleive that it has to do with damage to a nerve I, have been readin some info on irritable larynx syndrome and saw info on central hypersensitivioty disorder which led me to the possible damage to a central nerve.
Hope this helps

[Delena2]

Yes, I think the burning may have something to due with thyroid and the nerves.  I'm in intense burning pain in my throat, esophagus and the back of my neck.  I've had severe thyroiditis the past 5 years and I think it damages the nerves.  I've been since by many differnt doctors and specialists and no one has found anything to cause this.  I'm on thyroid T4 and T3.  I started them this year and I think the pain has increased on them so I'm thinking this is thyroid related.