muscle twitch in right palm/base of thumb

[canyons]

58-excellent health-run/lift/stretch every day--over past 2-3 yrs had a succession of unrelated (except to age?) aches:SI joint, wrist tendonitis, plantar fascitis and these have caused me some anxiety (occasional xanax--ave: 1/week over the period).

First notice was when physical therapist was realigning wrist and we both noticed palm/thumb muscle twitching. Twitch goes from base of thumb to wrist almost to the point where the PT was pressing on the scafoid bone (I believe).  This was ~1 mo ago. Noticed it again about 10 days later, muscle twitched several hours. Now sometimes it is for a day and enough to affect sleep.  At first, seemed to cease with a glass of wine or 1/2 of a xanax but now seems to persist through that too.  No pain, no loss of strength. No loss of motor control except the tremor from it if I'm holding something very light or loosely (newspaper). Is this possibly caused by the manipulation in the wrist?  Is this benign fasciculation syndrome? Can I treat this in anyway?