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Has anyone had the Synvisc injections?

by Kikko, Apr 11, 2007 12:00AM
I have had left knee problems for at least 4 years now.  Dr. has given me quite a few injections into the knee.  Now he is suggesting Synvisc injections. This is injected once a week for three weeks and is supposed to provide up to 6 months of knee pain relief. I was wondering if anyone has had this treatment and if there are any side effects from it?  And does it really work and last as long as they claim?????  Thanks,  Kikko
Member Comments (95)

by kneeone, Apr 19, 2007 12:00AM
I just received my first shot of Synvisk on 4/18/07, and within minutes my knee pain was completely gone.  There is still a little stiffness, but so far I feel like my knee's are new.  I still have 2 more shots to get and I can't wait to see how I feel....  I was told that for some people it works on the frist shot and some it takes all 3 shots before it works.  i guess I got lucky.  I can now continue playing softball as before the shots I couldn't run, now I am as fast as I used to be...

by Kikko, Apr 19, 2007 12:00AM
To: kneeone
thank you for the encouraging information.  I hope you continue to do well with it.  Did your doctor tell you how long it will last and how often you can get the series of injections?  Kikko

by kneeone, Apr 20, 2007 12:00AM
The shot last's up to 6 months, but I need to ask how often I can receive the treatment.  I played softball last night and I had absolutely no knee pain and I was able to run and slide, something I couldn't do for a few years now.  It has made playing soooo much more enjoyable.  I wish that I had known about this treatment sooner.

by Kikko, Apr 20, 2007 12:00AM
To: kneeone
I am so happy for you.  Just don't overdo and cause more damage.  If you find out more about the treatments, do post it.  I won't be seeing my Dr. for another few weeks.  But I do think I will give it a try.  I might not get as good results as you did.  I am 66 yrs old.  And if you are playing softball, you are young! Good luck to you.   Kikko

by kneeone, Apr 21, 2007 12:00AM
I am 36, but my doctor told me that I have the knees of an 80 year old.  There was an elderly lady that my doctor said was 86, getting the same treatment as me.  I have had 2 knee surgeries and the cartiligde is dissintigrating so I am on borrowed time.  But I will let you know how the other treatments go next week.

by kneeone, May 03, 2007 12:00AM
I received my 3rd and final shot yesterday, and I feel like a million bucks !!!!!!!!
  Hopefully this feeling will continue for over the 6 month time frame.

by Kikko, May 05, 2007 12:00AM
To: kneeone
Hi Kneeone,  So glad the shots have worked so well for you.  Saw my Dr. and he said I first needed to have the knee joint "cleaned" out with an arthroscopy as cartledge wear is very visiable on the exrays.  Had that done and now just have to wait for swelling to go down before he can start the injections.  I will be very happy with even some relief and postponing the fact that I will need a replacement with a few years.  I'll stall on that as long as I can!  Keep up the good work and God bless you.   Kikko

by bracs girl, May 18, 2007 12:00AM
yes i have had the synvisc injections and that was one of the best things!!!!!
i have had two series in my right knee. each series lasted 6 months. now i have a pretty bad problem with my left knee and i am trying to get a prior authorization from my ins. co to approve it, however they want 90 days of conservative therapy befor they will approve it. i work in a pharmacy, i'm trying to come up with the money myself to get started on the left knee. i can not beleive ho much better my knee was and the things i could that i had not been able to

by Caren Kosen, May 31, 2007 12:00AM
I had the injections in both my knees 2 days ago. Immediatly after the injection one of my knees actually started to buckle. I have had pain in both knees since. I called my MD who recommended to ice them. Last night my knee felt like it popped out. I have read all the side effects and this does not seem to be the norm. I have a appointment with my Orthopedist today. I am very reluctant to have the next set of shots next week. I seem to have more pain now then I did prior to the shots..Both knees are increadably stiff as well.

by alexjbip, Aug 29, 2007 10:05PM
To: My knee esperience
I didn't have too much pain in both knees but they felt like "rusted hinges" so my Ortop. Doc. recomemended  the Synvisc injections, tomorrow I am going to get the second injections and next week the third one and last. So far so good. After the injecctions I got a little pain but not a bid deal, I hope this will be a final for at least couple of years. Am I too optimistic?

by Sports fanatic, Sep 06, 2007 08:58AM
I have been doing knee injections for about 6 years now. I did Synvisc the 1st yr.,Supartz the last 4 and this yr. my Dr. recommended Synvisc again. Did well for the first 2 shots. I just had my 3rd two days ago. Woke up this morning and I could not walk. I had to call in at work. I have never had this problem before the shots have always worked great lasting up to a year. However this time is a totally different exp. The pain is almost unbearable. I am still waiting on my Dr. to call. I am wondering if I should not have stuck to the Supartz.                                                                                

by vega_mite, Nov 23, 2007 06:20PM
I had a referral to an orthopod to get the Synvisc injections, but when I saw him he told me they didn't work.  As a result I didn't get them.

by rudie588, Jan 14, 2008 08:53PM
Started with a work injury to both of the knees.  Then I had scopes on both knees.  Therapy didn't work to well. Arthiritis followed.  I just completed 1 session of synvisc ( 3 injections in each knee for three weeks).  Didn't get much relief.  My right knee swoll up and caused so much pain.  My doctor recommended a bone scan to make sure there isn't a tumor on my knee. (They saw a spot which could be from the injection site or maybe a tumor).  I am pretty much bed ridden.  I will not get those shots again.  I am really disappointed that they didn't work.  But I am happy for all of you that have had success!!!!!! Today he gave me a cortisone shot in my right knee.  Hopefully my scan comes out okay.  But what happens after that is questionable.

by Shannon388, Mar 01, 2008 11:21PM
To: Anyone!!!!
I'm sitting here reading all these pros and cons regarding Synvisc and wondering what to do for my knees!  I'm 45 yrs old and have had problems with my left knee since I was 15.  I have NO cartilage in my left knee due to the surgery they did when I was 15.  (gymnastic injury)
Of course...that surgery set it up for arthritis.  Over the past 7 years or so both knees are getting worse..  The dr. wants to wait until I'm older for the knee replacement, but it's only a matter of time.  He also says, Its really up to me when I have the replacement, but I need to wait until the pain is an 8, 9 or 10 everyday.  If I fall or even step off the curb the wrong way and bust it wide open, I'll have no choice but to do it.  The stiffness in both knees is sometimes unbelievable and I can't sit on the floor or get out of a chair or off the couch without the help of my arms or someone pulling me up.  It's crazy.  I want to try the shots, but I'll have to pay for all of it.  My ins. will not cover the injections.  But they'll pay to have a knee replacement.  Now, that makes perfect sense! I'm nervous and want to make the right decision.   Any ideas?
Shannon

by ronmac, Apr 01, 2008 11:47AM
I am 57yo.  Had arthroscopic knee surgery 3 yrs ago to "trim up" the meniscus - the pain was worse after surgery than before.  Doc said it was due to arthritis.  Several months later, he recommended synvisc and I recd the injections.  I was disappointed when my knee failed to respond, but  doc recommended a cortisone injection to "supercharge" the synvisc.  I was skeptical, but figured I had nothing to lose.  Knee felt good immediately after the cortisone, which is normal.  To my surprise, however, the knee continued to feel good and two years later still feels ok.  Synvisc + cortisone booster worked for me!  Good luck to everyone..

RonMac

by Nick115, Apr 01, 2008 05:54PM
I went in for knee surgery to trim up the meniscus which had a horizontal tear.  After the surgery I had more pain than before ... it has been almost 8 months now..  The doctor recommended I take some supplements - Vitamin C and Calcium w/vitamin B with a recommendation for Synvisc as well.  I feel that I want to wait a bit longer because my knee is just beginning to feel a bit better ... don't know if it is the amount of time or the supplements but I am going to wait on the injections for awhile.  Oh BTW I am 54.

Nick

by skaler, Apr 07, 2008 02:38PM
To: Anyone
My Mom is 92, and has been suffering with knee and leg pain for quite a while. She's been taking Aleve with diminishing results. I got her some Celebrex. No improvement. She states that her pain is mostly while standing. She can sit, and even has an exercycle which she uses as best as she can. She did try a cortisone injection and states that the pain was worse, if anything. At her age, I think knee replacement is out of the question.  I wonder if there are some "older" folks out there who have had good results with synvisc?
From all of the comments posted here, it seems a toss-up. There are as many happy results as there are disappointments.

by wellness4him, Apr 11, 2008 04:15PM
I had three synvisc shots 2 months after arthroscopic surgery. Within 24-36 hours of each shot, I was in intense pain. The doctor said there is no relationship. After the third, I couldn't walk for 2 weeks without a crutch. I had a NAET treatment for my allergic reactions which reduced the pain intensity greatly. The ANET testing showed that it affected my skeletal muscles, joint tissues and body fluids. No wonder it felt like he shot battery acid into my knee and lower leg.

I do not recommend them, especially if you go to a doctor who refuses to see that allergic reactions are a reality.

by babysteppeon, Apr 11, 2008 11:38PM
To: kikko
Have you had x-rays or an MRI done to see if there is something going on before you get the injection?  Have you had an injury to bring pain on?  MRI's are excellent to see muscles, tendons and ligament, meniscus, and can even see bone lesions which x-ray can't show.

by RaineyDay, Apr 18, 2008 01:08PM
To: anyone
Are these injections used for other joints, perhaps thumbs, that are damaged by osteo?

by Sherryelyn, Apr 21, 2008 11:21AM
Although it sounds like people can have allergic reactions to Synvisc, and that perhaps some doctors aren't trained well in giving the shots in the right locations, I know of three people who are doing extremely well after receiving Synvisc injections. My coworker friend at our healthcare group had heard about Synvisc from another coworker at her 2nd job with another healthcare group. This woman told her that after she had received her injections, her knee pain was gone, and it had been about a year or so. So, my friend, who had been going frequently for cortisone injections, opted for Synvisc.  After her three shots she was feeling GREAT, and she  has not had pain for a year now. She has not required further injections.

I also know a man who had it done two months ago, and is doing great. However, I had to tell his wife that he must stay off of his feel for a couple of days or so after each injection, as he had planned to go back to work the way he would after a cortisone shot. It is not the same thing at all, and you must stay off of your feet to allow this fluid to settle where it needs to. He did as recommended, and he is feeling terrific!

People run into problems when they don't heed the instructions to stay off of their feet and keep their leg elevated for a couple of days. They may also run into problems with doctors who are not trained well enough to hit  the correct injection sites, and who may inject too much in one spot. You have to find a well trained orthopedic surgeon to do this.

I have heard of three success stories, so I am recommending Synvisc to others. I am surprised that they say it only lasts "up to 6 months", as my coworker has been fine for over a year, and her coworker at her other job has been fine for two years.

  

by browneyegirl58, Apr 26, 2008 05:29PM
I am 49 yrs old. I have had knee problems for 15 years.  Arthoscopic surgery on both knees done 1999 and 2001.  I have continued to have some pain but I have managed with medications.  

One month ago I had Synivsc injections in my right knee.  The right knee was the one that was most painful.  I have no cartiledge left and rubbing bone on bone with several bone spurs.  I have had some relief.
I had my first injection on the left knee 1 week ago and it is great.  No pain whatsoever.   Two more shots to go.  

My insurance coverage was great too.  I had to pay $100.00 copay for a Synvisc.  (box of 3)  each box  $100.00

My question to others that have had these injections is if they experienced any depression with this medication.  I have also battled depression for a number of years and after the first injection on the first knee I began to have a dark cloud hovering.  Those of you who suffer depression will know what I am talking about.  Each injection I would get the depression was greater.  

Has anyone experienced this.  

by joekneedshelp, Apr 29, 2008 11:23AM
To: browneyegirl58
I also have "bone-on-bone" on the medial miniscus. My Dr. says Synvisc is not as effective in a "bone-on-bone" situation. What were you told about the expected outcome? Why did you do it?

by littledragon133, Apr 29, 2008 04:21PM
To: browneyegirl58
Had my last Synvisc shot about three weeks ago.  It hasn't helped at all,
actually feels worse.  My doctor told me before I even got the shots that
they only work in 50% or so of the cases.  If your arthritis is advanced,
less chance of working.  Mine is very bad but tried it anyway. I am so glad I only did it in one knee.  He told me to do that in case it didn't work.
littledragon133


by DrRakeshMD, Apr 30, 2008 12:35AM
To: Kikko
Hi Dear

Synvisc is used to relieve knee pain due to osteoarthritis (OA). It is approved for those patients who do not get adequate relief from painkillers such as acetaminophen, or from exercise and physical therapy. Synvisc is injected directly into the joint to restore the lubricating properties of normal joint fluid. The therapy is generally well tolerated. However, it may not work for everyone. The side effects most commonly seen when  pain in knee, swelling and/or fluid buildup around the knee. Before using Synvisc, it should be ascertained if one is allergic to products from birds such as eggs, feather etc.

Best..

by browneyegirl58, May 04, 2008 08:48PM
To: joeneedshelp
I go tomorrow for the 3rd injection of Synvisc in the left knee.  I am doing rather well now. The injection I had last week was the most painful as of date.  I am walking alot better.  Has been a month since I had the Synvisc in right knee.  Hope to be doing alot better soon.  

My doctor says that the Synvisc was not as effective for the bone on bone but this was my only option.  He does not want to do surgery until I am older but  he said it was up to me when the pain got to the point where I could no longer stand it.  I wanted to try the shots to see if I could get the relief.  I have tried several options, pain meds,  and pt.  This was my last resort before surgery which I will do on the right knee if the Synvisc
did not work.  

I still have pain especially in the right knee but not as much as before.  
This was the best choice for me at this time.

by browneyegirl58, May 06, 2008 05:20PM
To: all
Update!  I went for the last Synivsc injection on left knee today.  Shot was not painful at all.  I guess when you have knee pain you can pretty much take alot of pain.  As I have said before I do still have some pain in right knee (worse) but completely pain free in the left.  My physician also gave me a sample of a new medication called Voltran Gel for OA.  I put that on the painful part of my right knee and it works pretty good.  I left the doctors office after the last injection  and I put this gel on both knees  and went to see my daughter's senior project at our Bancorp South Arena.  I did great.  This was the last resort for me before surgery.  I wanted to try it and left knee is better than the right knee but with this new med I may be ok for a while.  I am very excited about the injections and the gel as well.  

by wellness4him, May 07, 2008 10:38PM
To: Everyone
It's been a month since I posted in regards to my adverse reaction to Synvisc. My injections were given following artho surgery for slight men tear, synovial joint capsule damage, a floater and articular cart damage all from a fall.

Although the NAET allergy treatment has helped to reduce the intense, feels-like-battery-acid-is-eating-my-flesh kind of pain, I still can't ride my bike (which I used to commute on my bike everywhere at least 20 miles/day). I still can't walk for long, (which I'm an avid hiker, skier, explorer kind of gal). I am 43 years old, and all I can say is that Synvisc has ruined the last 3 months of my life...and I'm still not better.

I'm glad that Synvisc has worked for so many people, but don't think Synvisc is a risk-free treatment. Watch carefully for warning signs of a reactions, AND don't depend on your doctor to STOP based on your symptoms...this is a huge money maker. (sad but true)

I'm totally disappointed in this whole experience.

Someone tauted MRI's in an above post. Beaware: I had 5 points of injury from my fall, and ZERO showed up on the MRI.  My surgery was a success, praise God, but everything else has been a nightmare.

by browneyegirl58, May 11, 2008 10:05PM
To: All
Update to all about my last Synvisc injection in my left leg.  I am so blessed.  My knee is pain free walking.  I only have minor pain when walking up stairs.  The right knee is still painful but with the Voltren Gel applied to it as well as some pain meds I will be able to function.  

Synvisc may not be for everyone but it is what was good for me.  I will do it again when the time comes.  

If anyone considering having the injections and need some questions answered just let me know.  I will be on this forum daily.

Good health to all!

by 3456, May 12, 2008 12:13PM
To: kikko
Hi, I'm 68 years young, have bad knees for the last 15years.
I had the Synvisc infection last Aug 2007. I will be having the next set of infection in June 2008. I have the infection in both knees at the same time and get up and walk out of the office.
Just a little follow up, I need both of by knees replace, and would not do it now because of family's needs. Will have the knee replace next year. and with the Synvisc, I would have had to get the surgery earlier.
It worked for me.
Good luck.

by browneyegirl58, May 12, 2008 05:29PM
To: kikko
Your comments were very interesting  to read.  I am one month out on the right knee(worse) and one week out on the third injection on left knee.  I was out and about today and I actually watched myself walk as I was going into a store.  I did not limp as much as before and I somehow seem to walk kinda normal. That is a first for me in a long time.  I didn't really have difficulty picking my leg up to set up on a curb.  Those of you know what I am talking about.  Those that do not know ( well-are blessed).  

I am applying the new medication Voltren Gel to my knees and it really helps too.  I have a friend that had knee replacement on 4/15/08  and I take her for her office visits and our doctor gave her a sample also.  She was going to have her other knee done in Nov 08 but now says she is doing much much better using the Voltren Gel and now may delay surgery for now.  May not work for everyone but we are two Mississippi gals and it has helped us.  

I have a question.  My physician says the Synvisc shot last 6 months.  Has anyone had an experience where they last longer than 6 months?  Just curious.

by incredibelle, May 12, 2008 05:58PM
To: kikko
I had two series of Synvisc shots 4 yrs ago when every impact made me cringe.  I have not needed any more since that time, and I now have a pain free stable knee (initial issues were medial meniscectomy; acl replacement) that continues to amaze me.

Good luck for continued effectiveness.

I think that the reason that I continue to be pain-free is that somehow, the volume of the injections changed the biomechanics internally.  Once that happened, I became good to go.....and go......and go.  So:  bottom line:  Although the injections themselves are painful, the long-term effectiveness in my case completely warranted them.

by kneeofight, May 14, 2008 02:31PM
To: kneeone
I am 38 years old and have had an arthroscopy on my left knee.  I had a tear of the meniscus as well as scar tissue, floaters and osteoarthritis in the knee.  The orthopaedic surgeon told me that the surgery would take about 45 minutes.  It actually took nearly 3 hours.  After the procedure, he told me my knee was "a mess" and one of the worst he'd seen since practicing medicine.  Like one of the others' posts to this site, the MRI and x-ray did not reveal all of the damage I've had to my left knee.

Before the surgery, I could not ride in a car for more than about 20 consecutive minutes without having to stop and get out to move and stretch my knee.  Two weeks before the surgery, I was calling my orthopaedic surgeon to see if he could move me up on his surgical schedule because the pain was so chronic and intense.  After the surgery, I've had a dramatic reduction in the pain level.  Like one of the others who've posted on this site, my orthopaedic surgeon does not consider me a candidate for knee replacement surgery now due to my age.

I am mostly mobile but have mostly stiffness in both knees and somewhat limited range of motion; particularly in my left knee post-surgery.  I am looking for a therapy that will restore some more of my range of motion in both knees as well as the stiffness.  My pain level in my left knee is actually pretty moderate.

My right knee has not approached the leve of paid I had in my left knee prior to the surgery.  I hope the right knee will hold out for a few more years without necessity of arthroscopy or other procedure.  However, both knees still ache, swell, and stiffen.

I've been taking Osteobiflex, and I've noticed some improvement in the stiffness and achiness.  However, I'd like to hear comments from anyone posting on this site about not only Synvisc treatments but other treatments available for treatment of osteoarthritis in the knee joints.  My symptoms are more achiness, stiffness, and limited range of motion instead of pain.  Thanks.

by legs96712, May 22, 2008 01:28AM
To: anybody
I just completed my last (third) injection, and there is no difference, same amount of pain.  The cortisone shot really made a difference for the Bursitis, but synvisc....No difference,still in a knee brace

by browneyegirl58, May 25, 2008 09:00PM
To: legs96712
I hope you get some relief from the synvisc.  It did take about two full weeks after the injections  to get to feeling better.  I am back where I started with the right knee. I am about 1 1/2 months out and I am having alot of pain. I have several bone spurs as well as OA.  My left knee is great.  Never gives me pain or stiffness.  Give it a little while longer to absorb in the knee.  
Hope you will do well.

by doorsfan, May 30, 2008 01:10PM
To: legs96712
I had my first synvisc shots in my left knee wich had 2 operations,synvisc to me was a life saver,it lasted 2 yrs,only after driving a car with a clutch did it start hurting again,I got the second shots 2 yrs ago again life saving relief,but thats the problem,.it works too well and surgeons and pain docs dont like it,no profits from ur pain relief.     last year the osteo started in my right knee and I have been to 3 doctors in a row who refused to give me the shots,trying to set me up for unnesesary surgeries,back & hip,neither had any problems.  Beware if they try to give u a series of 5 shots of something they say is like synvisc but its not,the other stuff does not work and the last "doctor" left me in a wheel chair in agony,I am right now in the process of filing a complaint against him with Aetna insurance who know what these QUACKS are trying to do.I have 2 friends one in New Jersey one here in Houston who always got synvisc and now they got the same screwing from their docs that I got

by BADBONES169, May 30, 2008 06:22PM
To: legs96712
The injections did work for me I had 2 series of injections the Dr's. like it because it is non toxic and does no damage unlike cortisone.The one thing I noticed after 5or6 months the pain came back fast,it was not a gradual increase

by camparitonic, May 31, 2008 09:07AM
To: legs96712
I just turned 70 this year and suddenly started to have pain in my rt knee, never had any problems before, skied and biked, always exercised with weights and low impact aerobics, have taken glucosamine/chondroitin for years, eat the right foods (lots of veggies and fruit, no simple carbs - well, very little every once in a while) complimented by many of the "right" vitamin supplements and bio identical hormone replacement.  

A month ago, the pain was so intense, I could no longer exercise or take walks.  I tried a cortisone shot -- didn't do anything for me. I was talked into arthroscopic surgery to "fix a couple of meniscal tears" which was supposedly no big deal and was promised to give me relief practically "instantly" after I healed from the surgery.  I hate it when the surgeon lies to you.  Here I am four weeks later and the pain is worse at times and it's there 24/7. Synvisc injections were not an option, I was told, since I also have "some" osteoarthritis.

I have since consulted another orthopedic surgeon who showed me in his xrays that the cartiledge in my knee joint is practically shot (I have about 1 mm where there should be 5 mm), declared that I have severe osteoarthritis and I am now looking at a knee replacement.

If you're still with me, please understand that the injections are simply a stop gap measure that will tide you over for a while, and so is arthroscopic surgery -- I have read reports that seriously question the validity of having the scope surgery done, since more often than not, it doesn't solve any problems and tends to cause pain for a prolonged period of time -- my osteopath speaks of 6-12 months!  And he's had both knees done as a young man due to sports injuries -- so he knows from experience.

For reasons of counter indications, I can only take Tylenol, which doesn't do much for the pain, but I am on Celebrex and I tried Ultram 100 mg (200mg was way too strong for me) which makes the pain bearable, but constipates me to the point of compaction.  I've added a large amount Psyllium husks to my diet to combat this.  Elevation (above your heart) of the leg and ice helps some. So does walking with a cane -- be sure to use the cane on the opposite side of the problem knee.

I recently received a prescription for Lidocane patches (used primarly to relieve the pain of Shingles) which I wear on my knee for 12 hrs during the day and that seems to hold me practically pain free.  I would recommend it to anyone suffering with knee pain who doesn't want or can't take oral pain medication.  

A word of caution, though, even if the pain lets up, don't overdo it -- remember, the underlying problem is still there and you might do more damage.  Osteoarthritis cannot be cured -- at least I haven't heard of anything that restores the cartilage, so knee replacement seems the only option left.  Fortunately, the artificial knees now last beyond 25 years -- In my case, it will probably outlive me.

Tks for listening and good luck to you.

Karin

by BamaBat, Jun 06, 2008 02:12PM
To: All Readers
Hi all!  I'm new to the forum but I'm glad to see so many people here talking about the Synvisc injections.  I'm 26 now, and back when I was 16 I chipped off the back of my kneecap in a rollerblading accident.  I'd had an arthroscopy to remove the bone chip and smooth the lateral meniscus, went through my post op therapy and was pain free.  About a year ago, I fell through a rotted board in a deck and suffered a second injury to that knee.  Immedately after the fall I had a massive hematoma and plenty of soft tissue damage, and with all the swelling -and me squirming- they were not able to get a clear MRI.  The initial injury cleared up but I was still left with a pain level of 1-2 daily, as high as 6-7 if I did too much.  Finally the pain got bad enough on a daily basis that I started monthly Toradol injections, which only helped at first.  I was started on a Medrol Dose Pack, Celebrex and Darvocet after several Toradol injections failed to make a continuous improvement.  The Medrol made a noticable improvement but it faded a few weeks after I finished the pack.  Celebrex, I think, is the only thing keeping me from going out of my mind.  A gall bladder removal has made Tylenol very hard on my stomach, no matter what coating or formulation, and so I have been mostly unable to tolerate standard pain meds.  Ultram ER 300mg has done well for a daily pain control, but I have an emergency supply of Vicoprofen for flare ups.  I've also graduated from ACE wrap, to knee sleeve, to a vicious metal and velcro contraption that leaves a bruise on my knee.  My ortho has determined through X-Ray and MRI that I have (forgive the spelling) condromalyisa from previous surgery, a baker's cyst, dislocating patella, and although not clearly visible on MRI, he suspects there may be a meniscial tear in there somewhere that's caused the cyst.  So far I've been through several weeks of thearpy (in the pool, because I refuse to go to Helga's House of Pain) and am due to start my Synvisc injections this afternoon.  I've had cortisone injections before on other joints and did NOT respond well to them, and am now very nervous about injections directly into the joint.  I am heartened by all the positive results many of you have had, but I seem to get the feeling that you either love Synvisc or hate it, and that while it may relieve pain it will not stop a looming arthroscopy, only delay it.  My stomach is in knots and my fingers are crossed.  Will let y'all know what happens next!  

Thanks for reading,
Nicole
Bama's Own Batgirl

by nanavlb, Jun 10, 2008 12:38PM
To: All Readers
10 years ago, I had ACL reconstruction surgery on my left knee. 6 years ago, I received the Synvisc injections in that knee.I have been almost pain free until about 6-8 months ago! WooHoo!!! I just went yesterday for my first injection of Supartz (in both knees) which my Dr. says is more effective than Synvisc. We'll see!

God bless all of you! Hang in there!
Vickie

by BamaBat, Jun 13, 2008 02:35PM
To: All Readers
Well, I ended up getting Orthovisc instead of Symvisc, don't know what the difference is.  However, got some significant pain relief for a few days, but it faded quickly.  Does it usually take all three injections before permanent relief is achieved?  Or is this a sign it probably won't work for me?  Any thoughts would be appreciated!

Thanks,
Nicole
Bama's Own Batgirl

by Lori416, Jun 15, 2008 12:21PM
To: All readers 6/15/08
Hi I am 2 weeks out from Meniscus surgery. I had a MRI prior to the arthoscopic surgery. After the surgery and during the Post op visit my surgeon tells me I might not get much relief, from pain as I have "moderate" arthritis in 2/3 of my knee. What was the point in doing the surgery at all??? I felt like asking. I have noticed little difference maybe 25% improvement. I did take an Aleve and did notice some relief. I am 59 and I am considering the injections as well. How long after Menicus removal does one feel better?  I have been told to Aerobics (water) and the eliptical trainer at the gym where I belong. I think all that is well and good, but it all just forestalls the inevitable. Knee replacement. UGH how I will dread going through such an ordeal.

by rekamelims, Jun 20, 2008 01:04AM
To: All Readers
Well, I go tomorrow (9:45 a.m.) to get an injection in my left knee;  56 yr. old male, overweight and sedentary ( very athletic before body started crumbling).  Had an MRI done after cortisone shot gave no relief.  Voltran was prescribed for pain and it worked but I'm afraid that cure may be worse than the curse.  I'm hoping watever drug they shoot in my knee will give me some long term relief without risking my overall health.  Dr. says i just have OA in my knee and after reading all these horror stories, wonder if the shots are a good idea.  Oh well, what's a guinea pig to do?  NO PAIN...NO GAIN!  Right?  Will keep you posted.

by Lori416, Jun 20, 2008 06:54PM
To: rekamelims
I am curious how your injection went? Did you get the Synsvisc? Curious minds want to know? I did Aleve twice this week. Once it worked fantastic the second time--nothing at all. I am seriously considering this for my left knee. I have "moderate" arthritis. Keep us posted. Thanks.

by tcrankwa, Jun 23, 2008 12:19PM
To: All
Hi folks!

I see many share our affliction.  Sorry indeed to hear this.

In Dec of 2004 I injured my left knee in a lifting accident (lifting too much).  I've had two a/scopes to repair the meniscus and shave the cartilledge and one open operation to remove some sort of cyst from behind my knee.  I've not been pain-free since that awful December.

The only relief I've had has been after cortisone shots. Unfortunately they only last a week or two.

I just finished having my third injection of Synvisc.  I got some partial relief after the first injection but not so much after the second and third.

Hopefully in the coming weeks I'll get more relief as the medication gets dispersed.  I look forward to reading about everybody's progress.


TerryC

by Lori416, Jun 25, 2008 06:08PM
To: All readers
Would anyone care to share what the cost of these injections are? I called my insurance company to inquire and they didn't know. They didn't have a listing on there schedule for it. Are they covered by any insurance? I know this can be ordered on a Canadian pharmacy for about $461.00 for 3 injections. Only problem is, who would do the injecting?? I am not that brave.

by Bamalady60, Jul 01, 2008 08:11PM
To: Lori416
I just had an appointment with my dr. this afternoon who suggested Synvisc. I asked if it was expensive---his reply "not if the insurance covers it; on your own, it's about $500." Don't know if that is accurate, but that's the number he called out.

by Jgdance77, Jul 10, 2008 04:43PM
Hello everyone. I am 30 years old, and I am a dancer. I have had 2 MRI's on my right knee. The first MRI showed a grade 3 meniscal tear, but it was not conclusive.  The second showed chondromalacia. Two MRI's and 2 diagnoses.  My doctor wants me to try the synvisc shots as a conservative measure, and if that does nothing, then he wants to do surgery.  I am a little scared about all of this. First of all, I am allergic to down feathers, so maybe it is not a good idea for these shots? Maybe I should just do the surgery. Anyone have any suggestions?

by Katmacrn, Jul 17, 2008 10:07PM
To: All Readers
I am a 60 year old Hospice Nurse, on my feet all the time.  I have had surgery to clean up my right knee, have had cortisone injections in the knee, used a bone stimulator for a cracked Tibia - now they want to do the Synvisc.  My question may sound silly, but I want to know how much this shot hurts, especially since it is a thick gel.  Any honest answers would be appreciated.  Thanks.

by BamaBat, Jul 18, 2008 09:37AM
To: All Readers
Finished my series of Orthovisc injections.  No improvement in my knee condition.

Good luck to the rest of you.

by tcrankwa, Aug 01, 2008 12:26PM
To: Katmacrn
It's not as bad as cortisone.  The amount injected is less.


TerryC

by hobblequeen, Aug 05, 2008 11:10AM
To: All
Greetings...I am 48, and at the age of twelve, I had surgery on my left knee.  A few weeks ago, I got up and my knee felt like it "blew out" to the inside.  I have gone to see an ortho, and he gave me a shot of cortizone (didn't last five hours), but I still cannot straighten my knee.  After having an MRI, he said that there really isn't anything left to repair in my knee, but he wants me to try synvisc.  I really get the feeling that he doesn't want to deal with me, but that is a entire situation all to itself.  I can't keep hobbling around, my job requires me to do alot of walking, and being up on my feet.  I'm kinda worried about what I should do.  Any suggestions?

by dgann, Aug 07, 2008 12:16PM
To: All OA Suffers
Hi!  I'm a 46 year old newbie to the forum and have my first Synvisc injection scheduled for next week.  Had my first scope in 1980 at the ripe old age of 18 (where ortho told me I had the knee of a 90-year old woman!) and got pretty good results.  Had my second scope in 2001 but really didn't get good results (bone on bone rubbing).  Have been told since 2001 that I will need a total knee replacement but they prefer to wait due to my age.  I'm now to the point where trying to get up after sitting for a while (car, motorcycle, couch, work, anywhere!) is a difficult task and my knee feels like it's "locking."  Even have constant pain (I have a high pain threshhold so it's more like a toothache) all day and it even wakes me during the night.  

Cortisone didn't work for me and doctor isn't giving me much hope for the injections but since insurance is paying for it I figure why not give it a shot.  Doctor says he prefers not to do replacements on "younger" patients because the expectations are higher.

by frankotunes, Sep 07, 2008 06:48PM
To: All
I have been diagnosed with a torn menicus in my right knee as well as osteoarthritis. I suffer a great deal of pain and have recently been prescribed oxycodone. It works well for the most part but when I lay
down at night my legs start to throb with pain and they burn as well.   My Orthropedic doctor wants to try Synvisc and has mentioned surgery
for the meniscus. Any thoughts on the Synvisc?

Franko

by earthguy, Sep 09, 2008 03:59PM
To: All
65 year old male in the landscape business working six days a week for many years.  I have worn out  cartiledge in left knee and was going to have an Oxford partial knee replacement, when something told me to get a second opinion.  Great doctor gave me a cortisone shot that lasted seven weeks (zero pain) and yesterday I had my first Synvisc shot (9 am). Shot hurt a little (3 or 4) at first, then nothing until about 5pm when I put an ice pack and took an Aleve.  Pain went completely away and had a good nights sleep.   Little pain today (a 2) after working a normal day.  Pain is different from original knee pain and more bearable.    

by spunkyfitlady, Sep 15, 2008 07:44PM
To: every one.
I execise every morning doing most likley way to many sqats and lunges. I think that the best thing to do is get some good supplements. I do not like doctors. I feel that they make you worse not better. I've been taking JOINT VIBRANCE by Vibrant Health it seems to really help my knee pain and swelling. You have to take it everyday you can't stop and you can buy it on line or at your near by GOOD HEALTH FOOD store not your neighborhood grocery store.  SOO to your health

Spunky fit lady

by lisa062061, Oct 03, 2008 09:37AM
To: anyone who cares to share
I am an active 47 year old woman with patellar femoral problems. I had 2 yrs of phy therapy back in 2005, aqua therapy, Iontophersis, ultrasound, deep massage, ice, etc...mri at that time said basically that I had mild OA, and the beginnings of some bone spurs. Normal ligatments, tendons, joint fluid, acl and meniscus--all ok! I was told to do strengthening at the gym and lose weight. I embarked on a weight loss program and lost 40 lbs over 1 1/2 year and started to walk and then joined a gym. I did the eliptical, the treadclimber, and weight machines until Oct of last year, I started 3-4 x weekly classes. Then my gym closed and I moved to another one, with better classes that challenged me more and I increased my routine with more sqats and lunges in a body pump class, and that is when my knee (l) acted up. A recent x-ray showed medial problems, and patella femoral pain, knee cap is hypermobile and they want to give my Synvisc, since I still have cartilage. Problem, I may need cortisone first according to my insurance, but I am considering the Synvisc----what do these shots fell like, I have heard horror stories........are they really that painful? I am currently in pt, taking Celebrex, icing and modifying my exercise routine.  thanks lisa

by prissysmom, Oct 07, 2008 03:09AM
To: HELP. IT'S LAWSUIT TIME FOR ME !
I had my last Synvisc injection on Friday, Oct 3rd at 10:00 AM at USC Medical Center in Los Angeles! By 5:00 PM by knee was twice the size, my muscles and tendons were cramping horribly, and I had spastic movements of my leg moving from knee backwards, I was in HORRID PAIN!! The worst! I called USC at 4:00 AM, as I thought it would all pass, but that was my mistake, should've called earlier! The doctor who gave me the injection DID NOT return my call, but an associate did! She told me to get to the nearest emergency room immediately! I now live 90 miles NE of L.A. we just moved here! Fortunately we chose our area because of excellent medical care, good banking and shopping, I am 65 and a retired music producer from L.A. area!  The hospital emergency room immediately gave me an injection for pain, my blood pressure was way high, my blood sugar was over the hill! They also  gave me a muscle relaxor, steroids, and antibiotic that are heavy strength. By 11:00 I could be released and purchased all the medicines at the local pharmacy. I spent Sat & Sunday flat in bed, my knee and leg could not work to stand or even move! I have a mobility small scooter. It got me into the bathroom, only sponge baths for me! I have been in agony ever since, I followed up with my general practitioner today and she suggested that Synvisc be sued and taken off the market, I could've and may still lose the use oof my leg! I am visting my Beverly Hills attorneys tomorrow! This is so wrong! Was this produce/medication/?? ever tested What were the test results that ended up to allow this product/medication on the market?/ It takes years and years of double blind studies to get any product/medication on the market? I will insist to see the test results before this product/medications was licensed! Any comments are welcome! If you are reading this to research this medication, take heed. If you have not had any injections, I WOULD STRONGLY RECOMMEND TO NOT TAKE THEM AT ALL! YOU ARE TAKING YOUR LIFE AND YOUR KNEE AND LEG INTO GRAVE DANGER!  STAY AWAY FROM SYNVISC! These doctors get huge fees to use this product from all insurance companies! They get up to $8,000 for thesse 3 inejections in my area! That is highway robbery! PLEASE TAKE  HEED!!!!

by BillyBe, Oct 31, 2008 03:54PM
To: All
I'm a 48 year old active male who had meniscus surgery on my left knee in 1977 and on my right knee in 1979 (old school on the left, arthroscopic on the right). I have experienced OA for several years now but has gotten worse recently due to increased activity levels.

I decided to see an Orthopaedic recently to determine where the medicine/technology is today and he recommended Synvisc (although he gave me a cortisone injection on that visit which did next to nothing for me). My insurance company only approved the left knee (it's worse) so I started with this two weeks/shots ago. The improvement was immediate. Two weeks later and I'm pain free and limp free. The joint feels cushioned and lubricated. Just incredible. Additionally, my right knee now feels much better because I no longer favor it so much.

This approach has worked great for me and I'm hopeful it will keep me off the table for many years.  

by midagebiker, Nov 03, 2008 01:40PM
To: Any and All
My husband and I both have a plethera of long term knee issues.  For him: OA, ACL reconstruction, bone-on-bone issues (46yrs).  As for me: Condromalatia- petella femural issues, maybe not sure meniscus tears, chronic swelling (44yrs).  But everytime either of us have stepped into our doctor's office they have pushed these shots without shame. My husband has had limited success with several 3x trails, reduced pain for 3-4 months but his knees have just slowly worsened.  I had no noticeable success from the shots, (can't remember the name brand, sorry) and much better success from working very diligently with a good PT.  

I do believe some doctors and PAs push these shots indiscriminately for any knee pain as they are big money makers. Our insurance have covered them so far, but it appear from our statements that the doctors office bills our insurance over $1200 for each shot.    I have an appointment with a new doctor as I got sick of refusing the shot treatment and hope to find a doctor interested in more then generating money.

BTW -  About the pain, neither of us have found the shots very painful.  

by Jane_Stillwater, Nov 30, 2008 12:28PM
To: Avoid SynVisc as if your life depended on it
  I wrote a blog entry (http://jpstillwater.blogspot.com) recently with regard to my initial nightmare experiences with SynVisc.  That was ten days ago.  Since then, my left knee has swelled up to twice its size, my calf muscles have become hard as a rock, I experience terrible burning pain below my knees because apparently the hyaironic acid has escaped my knee joint and seeped down into my legs, my ankles have doubled in size and I can barely walk from the bedroom to the kitchen.

    Does anyone have a class action lawsuit I can join?

Here's my blog entry on the subject:

"Jello Shots": From healthy Woman Warrior to old lady crip in just one day....

(Photos are of my father and mother on their wedding day and a birds-eye view of my knees when they first started to swell)



Boy, old people are my absolute heroes. Those people are truly BRAVE! I used to think that I was being all fierce and courageous to go off to Iraq and Afghanistan -- but that was a walk in the park compared to facing down the terrors of old age. I found that out last Saturday.

Recently I went off to a knee doctor to ask him if he could do anything to relieve the minor discomfort in my knees, and he replied, "We can inject gel into your cartilage area and that will help you a lot -- it will lubricate your joints and keep you pain-free for approximately one year."

You are going to inject gel into my knees? "Jello Shots!" I cried. "Go for it."

Well, I got a reaction to the SynVisc hylan and suddenly my left knee was all swollen, my right knee was the size of a cantaloupe, I was in incredibly intense pain and couldn't even walk. Was I now going to have to spend the rest of my life in a wheelchair? It looked that way.

"Jane, that's really a sad story," you might say, "but what's your point?"

My point is this -- do you have ANY idea how hard it is to not be able to walk, to live in constant pain, to have whatever active life you may have had suddenly disappear, to depend on others constantly for help and to get sympathetic looks from strangers at first and then suddenly completely disappear off their radar?

You have no idea how scary this is.

It took me a half an hour to shuffle across the street to the Berkeley Bowl to buy food because there was nothing left to eat in my apartment. One-half hour. They had to hold up traffic for me.

Once at the store, a clerk put me in one of those electric wheelchair cart thingies that the Bowl provides for little old ladies. "This isn't the REAL me!" I wanted to cry as benevolent shoppers got out of my way.

I filed a drug-side-effect report on the FDA's MedWatch website, but would doing that bring back my health? Probably not.

Then I shuffled off to my doctor's office and sat in the waiting room and cried. "Two years ago I was teaching school in a former bantustan in South Africa," I blubbered, "and now look at me!" I looked like all my doctor's other REALLY OLD patients, with walkers and crutches and aides and wheelchairs and canes.

I have just entered the Home of the Brave.

PS: Today would have been my mother's 96th birthday. She died in her sleep from a stroke at age 79. One day she was as healthy as a horse and the next day she was dead. Not so with my father. He died a long, lingering, painful death -- but during all the time that I watched my father suffer so much from prostate cancer and congestive heart failure, shrinking from a robust 6'1" to a tattered and grey 5'7" in less than a year, I never heard even one word of complaint cross his lips.

by frankotunes, Dec 09, 2008 07:18AM
To: All
I had my Synvisc shots a month and a half ago and I am now in very little pain. Also, much improved mobility and flexibility overall. I still need knee surgery but I am not in the agonizing pain that I was in.
Franko

by tyboro, Dec 23, 2008 06:39PM
To: All
Hi
  I am 58 have been extremely active as far as runnning,biking,weight lifting Tai Chi etc..About two years ago, the wear and tear,of knee joints became unberarable...I had to stop running, and climbing stairs became a painful chore...riding the stationary bike, was even painful...so I quit all aerobic exercise(except tai chi..which is really not) and decided that I would give my body a chance to heal itself..I also have been a health nut
vitamins etc..BUT this did not happen...went to primary care,then ortho...the PA suggested Synvisc...At first the knees swelled...and I thought, yea another scam to generate money..BUT about 8 week later, the pain I began rowing(machine)...and was eventually able to ride the stationary bike..Climbing stairs is "less" painful,BUT I do not have to crouch over while climbing them.
  Like all medicines it works for some but not for all..For me, the pain has been reduced to about  50%...and I am able to do the aerobic activities....(no running)...I wish everyon the best, and keep an open mind and a positive attitude to the product(if used) and life in general..if you cant do heavy aerobics, try tai chi or yoga...wish all the best!!!

by Mama2JRCx2, Dec 31, 2008 12:24AM
To: All
I've read every comment.

I had arthroscopic surgery the end of Aug 2008 for a meniscus tear.  The doctor also decided to clean out the arthritis PLUS reshape my bone while he was there.

I've had nothing but pain since.  Lots of PT, a shot of cortisone, still no relief.  Now he wants to do the Sinvisc injections, only I'm not convinced it is the thing to do.

Talked him into another MRI which I will not find out results for a week.

I'm WAY worse off after the surgery than before.  I think that Dr. need to give more information about possible outcomes prior to surgery, so people can make better choices.

The whole thing just stinks.

Donna

by Kaelesa, Feb 05, 2009 12:42AM
I've had severe knee pain for the past 5 years. I've tried phyical therapy, water exercises, and avoiding stairs altogether. My primary care doctor referred me to an Orthopedic surgeon recently. After an MRI on my right knee and x-rays of both knees, the ortho dr said my knees were "shot" and I should think about knee replacements (yes, both knees). I'm very overweight, and want to try losing that weight through lap-band surgery (but that's another story) before having my knees done. As an interim measure, I'm having the Synvisc injections in both knees. My younger sister had the injections in one knee and thought it worked wonderfully. She had her other knee replaced.

Anyway - I've had 2 of the injections and go for the last (3rd) next week. I didn't notice immediate relief, but my research indicated it can take a few weeks for the effects to be felt. My dr also told me that. Since the dr didn't give me an patient info about the injections, I went on Synvic's web-site  and printed out a copy from there. It gave all the relevant information about side effects, serious side effects, and states definitively that if a patient has any allergies to feathers, eggs, or poultry they should not have the injections.

When my dr gave me my injections, first he numbed the injection site with lidocaine. When the Synvisc injection was given, I felt pressure, but no pain. I had small bruising at the injection site, and minor swelling for the rest of the day and the next day - but ice and motrin helped.

I'm hoping the entire series will help me get through a few months with less pain. I feel bad that some of you have had such horrible experiences with the procedure. It sounds like lots of research and lots of questions would be the best way to approach this.

by 1nancy, Feb 17, 2009 09:25PM
To: All considering Synvisc
I'm 54 yr old female - had a problem/reaction to Synvisc. Few days after 3rd injection knee swelled/filled with fluid. Got it drained & got shot of cortisone. Doc said reaction to Synvisc would have been more severe & possibly infected. 3 days later swelled/filled with fluid again. Had it drained - this time kept it compressed, elevated & iced.  Got MRI - showed lots of fluid, signs of previous surgery (had meniscal tears & 2 scopes in last 5 yrs plus mild OA) but nothing else significant. It was still swollen, fluid filled, very uncomfortable & I was walking on crutches (what little I could walk) and laying in bed the rest of the time.  My doctor suggested I get it scoped again - but said he couldn't guarantee anything because the MRI didn't really show anything to explain swelling/fluid. Given I couldn't live with a chronically swollen, fluid-filled knee I couldn't bear weight on I scheduled surgery.  2 days before surgery - swelling/fluid is gone (after 2 - 1/2 weeks) and knee feels 90% better.  I called doc & cancelled surgery.  I can't help - after reading some of these posts - think I had a reaction to the Synvisc. Doc keeps saying NO - these posts say otherwise as do the side effects I read about on informational sites about Synvisc.  Don't know why my Doc is so resistant to entertaining that possibility - sounds like his reaction isn't uncommon.

by wellness4him, Mar 12, 2009 07:43PM
I'm a year out since my injections. I had a systemic reaction to Synvisc. I am still dealing with the symptoms throughout my body. I'm an avid outdoor person who, prior to the injections, pushed my body to it's physical limit near daily. Since the injections, I can't sustain a regular workout routine without hitting a wall that puts me down for weeks.

Keep in mind that if you have sensitivities to chemicals, this is not the product you should use. Also consider what is being injected into your body.

Formaldehyde and divinyl sulfone are both crosslinked in the processing and are allowed in permissible levels. Both are highly toxic chemicals, and the effects can be lasting.

Don't make the same mistake I did.

by 50yearsyoung, Mar 13, 2009 11:09PM
To: All
I am a 50 year old female with the right knee of a 75 year old woman. I have OA. I am 6 weeks out recovering from surgery for a torn meniscus. I don't feel there is any improvement. I had pt for 5 weeks following surgery - seemed  to get worse instead of better. I am considering injections, but am getting nervous after reading some of the comments.  Last year my right knee locked up, swelled and was very painful. I received a cortizone shot and it was like an instant cure. It has been fine ever since. 7 months ago my left knee went out. I had 3 different cortizone shots about a month apart but there was no relief. I thought surgery would fix it. While repairing the torn meniscus, the doctor discovered that I have severe arthritis and bone on bone in some areas. He says eventually I will have to have a total knee replacement. He said some people get relief from the injections while others don't. Did any of you ask your doctor what the success rate was of his/ her  patients?

Can anyone tell me after the injections, do you have to stay off of your feet and keep your leg up? How many days off your feet?

Thank you

by graolbai, Mar 14, 2009 12:42PM
To: All
I am 33 years old and have been recently diagnosed with chondromalacia in my left knee. Cortisone, steroids, and NSAIDS have done nothing to improve my pain. Had knee scoped in February to rule out any other problems. Nothing else was found, but doctor said my cartilage was very soft. He has now suggested Synvisc injections. They are not routinely used for my condition, but knee specialists in a major city close to where I live have been using it with good results. Is there anyone who has had the Synvisc injections for chondromalacia?



by Kaelesa, Mar 14, 2009 05:17PM
To: 50yearsyoung
It is recommended that after a Sunvisc injection you elevate you leg and stay off it for a day.  I found this to be true. After my first injection I ran errands before heading home and had more discomfort in my knees for the next couple days. For my next 2 injections I went straight home and stayed off my feet and didn't have nearly the discomfort as the first time. Ice and/or heat may also help for the first day or so. Good luck with your treatment.

by zephyrarose99, Mar 16, 2009 12:36PM
To: All
47 y/o female, torn cartiladge was removed from left knee at age 14 - arthritis started then too.  The cartiladge in my right knee is worn away completely.  I had my first synvisc injections in 1998.  I'm getting my 4th set of injections right now.  Tomorrow I get my 2nd round of injections.  After this 1st round of injections from last week, I couldn't walk for 2 days.  Even the slightest amount of weight on my knees hurt intensly - knees buckling, wobbling front/back - completely unstable feeling like my knees were being broken in half and ready to colapse beneath my weight.  The other times I had the injections, by the 2nd or 3rd I would have a hard time walking a day or two with one knee affected much more than the other but this time they both hurt intensly from the injections although I can already feel a more slippery surface for my bones to rub on, which is part of the problem.  Until the swelling goes down the synvisc can't settle in.  It must loosen up all the bone chips and joint so much that it makes my knees unstable.  I've used ice everyday since my first injections 6 days ago and my right knee is still having intermittent intense pangs of pain - enough to keep me from sleeping more than 2-3 hours at a time.  If I didn't know from experience that it does help my knees in the long-run (usually about 5-6 weeks after first injections is when I really notice the benefit), I wouldn't put myself through this.  IT IS EXTREMELY INTENSE PAIN & SWELLING for me anyway!  But I know it will get better.  Today I say I won't do it again but my only other option now is replacement knees.  The Dr. says my knees are too far gone for arthrosopy surgery to make any difference.  Does anyone have any information to disagree with that?  If so please reply.  Also, has anyone had the Gender Solutions High-Flex Knee for replacements done?  If so please reply with how they are doing for you.
Thanks,

Julie

by anxious in nj, Mar 16, 2009 10:13PM
To: All
The doctor’s office which is scheduled to do my injections on Friday told me that he doesn’t numb the area, that the numbing needles hurt more than the actual injection.

I have had dozens of injections in my big toes for years (ingrown toenails) and when done right, with freezing beforehand, the numbing injections hardly hurt at all. And I go to a wonderful podiatry practice, where they are very gentle and sensitive.

But I am still completely terrified of most needle injections, especially in certain areas. I can get very upset (racing heart, tears) at such procedures. Have never had any injections in my knees. I picked up the actual dosages, in packaged needle form (I can hardly bear to look at them), from my pharmacy. If I have to switch to another doctor, who will numb my knees first, can I just take the dosages to the new doctor?

I am also worried about side affects. I am an active, generally healthy 46 year old(problem is mostly the result of 31 years of patellar instability, which I have largely managed by making my knees stronger).  My husband can not drive for several weeks due to his own health issues. If there is a risk that the injections may cause side affects that effect simple things like driving and walking, that is a huge issue for us.

I can be very sensitive to routine medications such as antibiotics and painkillers (I avoid them as much as possible). Have never had anything like Synvisc in my body.

Is it unreasonable to call the doctor and ask him about the numbing and side affects issue? He seems quite keen on this treatment.

Thanks for any advice.

by Tammyvivi, Mar 24, 2009 04:31PM
To: All
I had meniscus repair Dec 2nd did all the right things, therapy, ice elevation, rest the rest of Dec and the first couple of weeks in Jan.  The swelling and discomfort continued and the Doc gave me a cortizone shot  I had a severe headache and some stomach upset for about 36 hours after the cortisone shot. It helped for a couple of weeks only.  Now I am scheduled for the series of Synvisc shots and am concerned that I may have a similar reaction.  Has anyone else experienced headache and stomach upset with the Synvisc shots?

by lildebbie49, Apr 01, 2009 07:50PM
To: nancy1 and All
I'm 59 and have been walking with a limp for a year now. I had the Supartz injections the end of December and beginning of January. For one month (mid January to mid February) everything seemed fine. Then for a reason I don't know my knee swelled and I am having trouble walking and it makes it hard to sleep. My doctor had put me on steroids for 7 days which did nothing. I saw the orthopedist 3 weeks ago. He kind of blew me off telling me that where I feel the most pain isn't where most of my problem is. He put me on an anti-inflammatory for 2 weeks. After taking them for 6 days the swelling hadn't gotten any better so I stopped taking them. I scheduled another appointment with him for the 17th of April. I don't think the swelling is from the injections since it took a month for it to happen but something is going on in the joint.  I think he should clean the joint since I have arthritis, bone spurs, chondromalasia petela and very little meniscus. If he does hopefully then my knee will fell better.

by lynn5775, Apr 01, 2009 09:33PM
I had the Synvisc injections about 2 months ago for chondromalacia patella.  They didn't help very much.  I am now scheduled for the HemiCAP implant surgery.  Has anyone had this surgery???

by statenisland, Apr 03, 2009 01:32PM
I had the synvisc shot in my Right knee over 2 years ago, and I  will be getting them again  in a few days. I was completely satisfied

by lynn5775, Apr 03, 2009 05:44PM
To: statenisland
What is the diagnosis on your knee??

by Cindy41755, Apr 13, 2009 09:22AM
To: All
I ripped my meniscus in my left knee while walking May 06, had surgery to repair it, dr also removed some arthritis, always was a little stiff, but flaired up bad about 2 months ago. received a cortisone shot, helped 2 days, then pain returned just as bad. After talking to my dr decided on synvisc shots. I've gotten all 3 shots, but pain is still there.Dr did tell me that it could take up to 6 -7 weeks to feel full effect, and that I could also get a cortisone shot. I read on the internet that synvisc works in about 50% of people, asked my dr this and he agreed with that statement. Trying to put off having  knee replacement as long as possible. I get up from sitting or riding in a car and I can't walk for a few minutes, has anyone else had this problem of having to wait so long to see effects. I am 54 years old  and bone on bone on the interior of my knee. Thanks.

by ash805, May 06, 2009 04:59PM
To: All
42 years old--surgeon wants to get me to 50 before knee replacements.  I'm a P.E. teacher, so that didn't sit well with me at all.  I'm due for my 3rd Synvisc injection this Fri.

After my 2nd injection, my knees remained very stiff and I am experiencing constant aching / pain in both knees.  Today, after work, I noticed a tingling / numbing sensation below my left patella.  Has anyone experienced this??

Diagnosis:  late stage arthritis in both knees; Baker's cyst in left knee.

by BadBreak, May 07, 2009 10:57PM
To: All
RE: Synvisc
Compound fracture of my right distal femur 1977. Osteotomy of injury site 1983. Lived with a high degree of pain since the original accident. I am not a candidate for knee replacement due to the severity and complexity of the injury and previous surgeries. Just had my 3rd Synvisc shot and I feel fine. My pain level has decreased by 90% since the 2nd injection and I am elated. I went into this very low expectations due to the fact that I am not a typical OA case. As Such I highly recommend consideration of the Synvisc treatments.

by JanPuppyLover, May 16, 2009 04:35PM
Hi--I am new here and would appreciate any information some of you folks with more synvisc experience have. I just had my second synvisc shot two days ago and have a third scheduled for next week.  After the first shot I had some pain, but not much after the second shot.  I am "jealous" of those on here who report almost immediate relief after the first shot.  Am wondering if anyone has had three shots and not have it work?

I had meniscus surgery on my left knee a couple of years ago and find that knee seems to "crack".  It doesn't buckle or feel unstable but a feeling more similar to "cracking" the knuckles on your fingers-- but "bigger."  Do you know if synvisc might relieve this as well?

I am very overweight, but was very active until the meniscus surgery a couple of years ago, and know that a good and rigorous exercise program is key for me keeping my weight under better control...sorta feels like a difficult cycle to get out of without getting my knees working again  :-)

Thanks for any of your thoughts and experiences.

Jan

by Kaelesa, May 18, 2009 10:52PM
To: Jan
I had all three shots, the last in Feb. and did not receive any noticeable relief. My ortho dr wasn't too optimistic about the synvisc working for me since my knees are bad enough that he says replacement is the only option left. I'm also very overweight and with my knees in such bad shape, walking for exercise is out of the question. I'm getting ready to have lap-band surgery on June 29. My ortho dr said that hopefully 6 months after that I could have knee replacements done and it would be successful, that my weight loss should be stabilized by then. I hope the synvisc works for you. Best wishes.

by jeanpeewee, May 21, 2009 07:00PM
To: anyone
Can anyone tell me what kind of cost is involved with the Synvisc injections?  I have no insurance, have had 4 cortisone shots, not working anymore, I understand there is a new Synvisc, which is only 1 shot?  any info would be helpful

by achyknees56, May 27, 2009 11:29PM
To: any one
I had synvisc a year and a half ago and it did wonders. I was at least 90% better. Then my knees had a bad flare-up and I had all three again. The third one caused swelling and pain. Now I am having facial pain and headaches. I don't know if it is caused by this or not. Has anyone else had this as a side effect.

by JanPuppyLover, May 28, 2009 10:11AM
It's been about 10 days since my third (and last) injection and I am not seeing any improvement yet.  sigh....

When I initially spoke to my orthopedic surgeon, he thought I was a good candidate.  I only have a very small amount of "bone on bone" and varying levels of wear in other parts of the knee.  I so hope that these shots start working soon.  :-(

In terms of side effects, after my first shot, I was pretty active walking around and ended up with some pain in the knee and quad area-- it actually felt "hard" right above one of my knees.  This all went away in a few days.

I took it easy after my second shot and had no side effects at all.

I took it easy after my third shot and had some swelling and pain in one of my knees which was alleviated with a couple of ice pack treatments and fine by the next morning.

Keeping my fingers crossed that I am one of those that these shots work for.

by cmodelbehavior, Jun 08, 2009 10:18AM
To: cmodelbehavior
I am a 48 yr old wife and mother and have suffered from OA for more than four years now. I was told it is OA but the pain doesn't seem like it to me. I have SHARP electric pain always in the same place on my right knee. Feels like a deep pain that you can't do anything with, it comes without notice and you never know how long it will last. Even waking me early in the morning with screams it hurts so badly. After two and a half years of cortisone injections, therapy and pain killers, I had arthroscopic surgery 7 weeks ago. Although my knee feels cleaner..my sharp pains are still present. I am going in tomorrow morning for another shot. I really wanted to know more about the synvisc, thinking it might be better for me than the cortisone, but after reading here I am concerned that it is too risky and I can't afford any more pain. I am already recliner bound and taking pain pills just to make it through the day. My husband and children need me.

I don't know if any of you feel the way that I do about it, but I don't think many doctors understand the pain or what we go through and how our lives are completely changed due to this pain. I got lucky and have a really great doc that understands me, after many that didn't. It's debilitating and keeps me from doing everyday activities.

I hope you all get the relief you need and I just want to thank those of you that posted here to help me make my decision easier..I will not be getting the injection of synvisc!

by JanPuppyLover, Jun 09, 2009 07:43AM
CModel...

I don't know what the sharp pains are about, especially while sleeping, so I can't comment on that-- I've not experience that.

In terms of being afraid of the shots causing side effects, I'd like to share my own  observation.  With absolute respect for the people posting here and their individual (and very informative) experiences, I doubt that people posting on this board are a true random selection of people who have had these shots.

Generally, though not always, people who are seeking advice/opinions are more inclined to do so if they are at the beginning of the investigation process (as you are) or are more likely to have had a negative than a positive result and are either seeking more information or trying to share their experiences with others.  

There is less motivation to come back to a board like this and post if you had a great outcome and are happily on your way enjoying life.  I truly appreciate all of those who have had a positive outcome who do take the time to come back and post.  And I think those who have had a less than optimal outcome provide invaluable advice to others thinking about the treatment.  I just don't think that one can necessarily judge how OFTEN people have side effects and difficult results by the numbers of what you see posted here.

My orthopedic surgeon is not only very well known in his field, but is long term personal friend.  He suggested that 70-80% of his patients who receive this treatment get at least some, if not total, relief for a period of time ranging from 6 month to a year.  He also told me that very few of his patients had side effects beyond some minor swelling for a few days.  This has also been my experience-- except for the instance in which I overdid it right after having my first shot.  And even those side effects were "ok."

Like most treatments or drugs that you take, a portion of the population is going to have side effects, some mild, some not so mild.  I am just suggesting that what we see on these boards MIGHT be a disproportionate number of those people who have had side effects.

By the way, I had my last of three shots a couple of weeks ago and am now starting to feel some improvement especially as I go up and down stairs.  

I am curious if anyone knows the medical or physical reason for why these shots take so long to work.  

The Synvisc website suggests that relief can take up to 8-12 weeks from the first injection.  Does it take that long for the Synvisc to work its way to where it needs to be?  I'm also noticing a reduction in the "moderate" swelling I generally have in my left knee and wonder if that might be part of what is going on.

Jan

by AmateurAngler, Jun 23, 2009 11:32AM
My first post - I'm 61 years old and had my first injection of Synvisc yesterday. So far so good - no reaction or pain and in fact, some improvement already. I spent some time evaluating the competing treatments and decided on Synvisc even though it does seem to produce a higher number of reactions than some of the others. I don't have any drug allergies and am fine with poultry products, so felt it would be a safe choice for me. I have a family history of osteoarthritis, and already have had hip surgery (hip resurfacing, not hip replacement) at age 52. I'm an avid fly fisherman and do a lot of walking and hiking, and just wasn't ready for a knee replacement at this point. I will post again as I have the second and third injections.

by Gary7154, Jun 23, 2009 03:51PM
To: Anyone
I'm 54 year old guy and am scheduled to have Synvisc injecktions starting on July 25th for an injury to my left "Ankle"! Has anyone ever heard of this treatment? I am suppose to have one of the best Dr.s in CT. I hope so. This is the last step before surgery...

Gary

by Dr Vinod, Jun 23, 2009 07:10PM
To: Gary7154
If you are not allergic to most of the substances then it is fine and this is the best possible way to avoid surgery. Always go conservative and hope for the best, till/if you require a surgery.  Take care!

by wellness4him, Jul 02, 2009 09:46PM
To: ALL
I highly encourage anyone considering Synvisc injections to go to this blog and read it first. Then make an informed decision.

http://synviscsurvivor.blogspot.com/

There are other options that DO NOT have toxic chemicals in them. There's also ozone and prolozone therapy that works great and promotes healing in the joint, not just a temporary fix like Synvisc. I went through HELL following Synvisc injections. Thanks to ozone and prolozone, I'm back to an active life.

Go to the above site and read more.

by wellness4him, Jul 02, 2009 09:55PM
To: Jan
"Like most treatments or drugs that you take, a portion of the population is going to have side effects, some mild, some not so mild.  I am just suggesting that what we see on these boards MIGHT be a disproportionate number of those people who have had side effects."

And that might be true, but no less worthy to warn others about this injection. It's certainly easy to minimize those who had terrible reactions, until it happens to you or someone you love. I personally know of 2 orthos who've stopped using Synvisc because of the reactions in their patients. A highly respected one who was Head of Orthopedics at a medical school said that one of his patients went to a knee replacement sooner...and he believes it was directly linked to Synvisc. I believ it happens more than doctors want to admit. Most hide the numbers anyway.

Until it's your life that is effected, it's easy to dismiss and minimize those who did react, and some whose lives have permanently been effected.

How do you know if you're going to one of "us" or not? Can you really know ahead of time?

by juditny, Jul 24, 2009 10:40AM
To: all
I am 59 years old.  I have been getting synvisc injections for almost two years.  I have osteoarthritis, bone spurs, partial tear in meniscus, an old thickness tear in my acl and a bone infarction in my right knee, which is my worst knee.  I get injections in both knees.  I need replacements in boyh knees but my doctor says I have to loose weight first.  I have lost over 100lbs. in the past few years, but he wants more.  I know of many people who are more overweight than I am and their doctors have said ok to surgery.  I am in a lot of pain, stairs are almost imposible and sometimes just simple walking is difficult.  I should have gone back for another series of shots but have been holding back.  Does anyone have a suggestion and does anyone else have a boneinfarction in their knee.  I would appreciate any comments.  Thankyou.    Juditny                                                                                                  












by Dr Vinod, Jul 24, 2009 08:46PM
To: juditny
For knee replacement the only criteria is not weight. Where are you in the BMI?

The stage of  arthritis and the years of suffering would determine the time to select knee replacement.  It would depend on the Physiotherapy after the replacement for complete recovery.

Your orthopaedic surgeon might be going conservative and is delaying the operation as this is the final option. Take care!

by bannanie, Sep 27, 2009 09:27AM
Has anyone had or know of anyone who has had synvisc injections to the shoulder. if so, please comment on your experience as there is very little data available.
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