The value seems to be high. However one test may be false, she will need to do another and confirm that it is rising. Even than, it will not be enough to say for sure she has cancer recurrence, it may be infection, heart etc. she will need to do a CT scan in addition to CA125 to make a sure diagnosis. It was right call to send her back to onco/gyn specialist. 6 years in remission is pretty good case! With best wishes for her, Alla
Unfortunately Ovarian Cancer usually comes back at some time. You can have no evidence of disease for years.
Alex